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Role of Acupoint Area Collagen Fibers in Anti-Inflammation of Acupuncture Lifting and Thrusting Manipulation

Evidence-based complementary and alternative medicine, 2017-01, Vol.2017, p.2813437-8 [Peer Reviewed Journal]

Copyright © 2017 Fan Wang et al. ;COPYRIGHT 2017 Hindawi Limited ;Copyright © 2017 Fan Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ;Copyright © 2017 Fan Wang et al. 2017 ;ISSN: 1741-427X ;EISSN: 1741-4288 ;DOI: 10.1155/2017/2813437 ;PMID: 28473863

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  • Title:
    Role of Acupoint Area Collagen Fibers in Anti-Inflammation of Acupuncture Lifting and Thrusting Manipulation
  • Author: Wang, Fan ; Cui, Guang-wei ; Kuai, Le ; Xu, Jian-min ; Zhang, Ting-ting ; Cheng, Huai-jin ; Dong, Hong-sheng ; Dong, Gui-rong
  • Silberstein, Morry
  • Subjects: Acupuncture ; Analysis ; Chinese medicine ; Collagen ; Drug dosages ; Extracellular matrix ; Fibroblasts ; Medical research ; Medicine, Chinese ; Morphology ; Rabbits ; Signal transduction ; Studies ; Treatment outcome
  • Is Part Of: Evidence-based complementary and alternative medicine, 2017-01, Vol.2017, p.2813437-8
  • Description: The role of the acupoint area collagen fibers in the efficacy of acupuncture lifting and thrusting (L&T) manipulation will be explored in this paper. 30 male NZW rabbits were randomly divided into 6 groups: sham operation group (Group N), model group (Group M), acupuncture without manipulation group (Group W), acupuncture L&T manipulation group (Group A), collagenase pretreatment group (Group JM), and collagenase pretreatment + acupuncture L&T manipulation group (Group JA). The bacterial endotoxin was used to generate the rabbit fever models. Acupuncture was applied at IL-11. The levels of IL-1β, TNF-α, and IL-4 and the rectal temperature were measured at 2 h, 4 h, and 6 h after modeling and the collagen fiber morphology at acupoint area was observed after 6 hours. Results. As compared with Group N, the levels of IL-1β and TNF-α in Group M were significantly higher; the level of IL-4 was significantly lower (P<0.05). As compared with Group M, IL-1β and TNF-α in Groups W and A were significantly lower and IL-4 was significantly higher (P<0.05). As compared with Group W, IL-1β and TNF-α in Group A were lower and IL-4 was higher (P<0.05). The collagen fiber in Group A was slightly rough, distorted, and fractured. As shown in studies, the endotoxin-induced inflammatory response can be significantly inhibited by acupuncture whose efficacy can also be significantly improved by the manipulations. Collagenase pretreatment may be the first receptor to the mechanical force of the L&T manipulation.
  • Publisher: United States: Hindawi
  • Language: English
  • Identifier: ISSN: 1741-427X
    EISSN: 1741-4288
    DOI: 10.1155/2017/2813437
    PMID: 28473863
  • Source: ProQuest One Psychology
    GFMER Free Medical Journals
    PubMed Central
    ProQuest Central
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