Language:

The use of propensity scores to assess the generalizability of results from randomized trials

Journal of the Royal Statistical Society. Series A, Statistics in society, 2011-04, Vol.174 (2), p.369-386 [Peer Reviewed Journal]

Copyright © 2011 The Royal Statistical Society and Blackwell Publishing Ltd. ;2010 Royal Statistical Society ;2015 INIST-CNRS ;Copyright Blackwell Publishing Ltd. Apr 2011 ;ISSN: 0964-1998 ;EISSN: 1467-985X ;DOI: 10.1111/j.1467-985X.2010.00673.x ;PMID: 24926156

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
The use of propensity scores to assess the generalizability of results from randomized trials
Author: Stuart, Elizabeth A. ; Cole, Stephen R. ; Bradshaw, Catherine P. ; Leaf, Philip J.
Subjects: Applications ; Causal inference ; Combinatorics ; Combinatorics. Ordered structures ; Control groups ; Designs and configurations ; Effects ; Elementary schools ; Empirical research ; Estimating techniques ; Estimation ; Exact sciences and technology ; Experimental design ; Experimentation ; Experiments ; External validity ; General topics ; Generalization ; Inference ; Intervention ; Mathematics ; Methodology ; Observational studies ; Outcomes of education ; Population estimates ; Population mean ; Positive behavioral interventions and supports ; Probability and statistics ; Random sampling ; Research synthesis ; Sampling methods ; Sciences and techniques of general use ; State schools ; Statistical analysis ; Statistical methods ; Statistics ; Valuation
Is Part Of: Journal of the Royal Statistical Society. Series A, Statistics in society, 2011-04, Vol.174 (2), p.369-386
Description: Randomized trials remain the most accepted design for estimating the effects of interventions, but they do not necessarily answer a question of primary interest: will the programme be effective in a target population in which it may be implemented? In other words, are the results generalizable? There has been very little statistical research on how to assess the generalizability, or `external validity', of randomized trials. We propose the use of propensity-score-based metrics to quantify the similarity of the participants in a randomized trial and a target population. In this setting the propensity score model predicts participation in the randomized trial, given a set of covariates. The resulting propensity scores are used first to quantify the difference between the trial participants and the target population, and then to match, subclassify or weight the control group outcomes to the population, assessing how well the propensity-score-adjusted outcomes track the outcomes that are actually observed in the population. These metrics can serve as a first step in assessing the generalizability of results from randomized trials to target populations. The paper lays out these ideas, discusses the assumptions underlying the approach and illustrates the metrics by using data on the evaluation of a schoolwide prevention programme called `Positive behavioral interventions and supports'.
Publisher: Oxford, UK: Blackwell Publishing Ltd
Language: English
Identifier: ISSN: 0964-1998
EISSN: 1467-985X
DOI: 10.1111/j.1467-985X.2010.00673.x
PMID: 24926156
Source: Alma/SFX Local Collection
RePEc

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

The use of propensity scores to assess the generalizability of results from randomized trials

Copyright © 2011 The Royal Statistical Society and Blackwell Publishing Ltd. ;2010 Royal Statistical Society ;2015 INIST-CNRS ;Copyright Blackwell Publishing Ltd. Apr 2011 ;ISSN: 0964-1998 ;EISSN: 1467-985X ;DOI: 10.1111/j.1467-985X.2010.00673.x ;PMID: 24926156

Searching Remote Databases, Please Wait