Language:

Genetic diversities of cytochrome B in Xinjiang Uyghur unveiled its origin and migration history

BMC genetics, 2013-10, Vol.14 (1), p.100-100, Article 100 [Peer Reviewed Journal]

COPYRIGHT 2013 BioMed Central Ltd. ;COPYRIGHT 2013 BioMed Central Ltd. ;2013 Ablimit et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ;Copyright © 2013 Ablimit et al.; licensee BioMed Central Ltd. 2013 Ablimit et al.; licensee BioMed Central Ltd. ;ISSN: 1471-2156 ;EISSN: 1471-2156 ;DOI: 10.1186/1471-2156-14-100 ;PMID: 24103151

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Genetic diversities of cytochrome B in Xinjiang Uyghur unveiled its origin and migration history
Author: Ablimit, Abdurahman ; Qin, Wenbei ; Shan, Wenjuan ; Wu, Weiwei ; Ling, Fengjun ; Ling, Kaitelynn H ; Zhao, Changjie ; Zhang, Fuchun ; Ma, Zhenghai ; Zheng, Xiufen
Subjects: Asian Continental Ancestry Group - genetics ; Biological diversity ; China ; Cytochrome b ; Cytochromes b - genetics ; Data analysis ; Deoxyribonucleic acid ; DNA ; Genes ; Genetic aspects ; Genetic diversity ; Genetic engineering ; Genetic polymorphisms ; Genetic research ; Genetic testing ; Genetic Variation ; Genotype ; Haplotypes ; History, Ancient ; Human Migration - history ; Humans ; Medical research ; Migration ; Mitochondrial DNA ; Multiculturalism & pluralism ; Mutation ; Phylogenetics ; Polymorphism, Genetic ; Population ; Sequence Analysis, DNA ; Software ; Studies ; Thermal cycling ; Uighurs
Is Part Of: BMC genetics, 2013-10, Vol.14 (1), p.100-100, Article 100
Description: Uyghurs are one of the many populations of Central Eurasia that is considered to be genetically related to Eastern and Western Eurasian populations. However, there are some different opinions on the relative importance of the degree of Eastern and Western Eurasian genetic influence. In addition, the genetic diversity of the Uyghur in different geographic locations has not been clearly studied. In this study, we are the first to report on the DNA polymorphism of cytochrome B in the Uyghur population located in Xinjiang in northwest China. We observed a total of 102 mutant sites in the 240 samples that were studied. The average number of mutated nucleotides in the samples was 5.126. A total of 93 different haplotypes were observed. The gene diversity and discrimination power were 0.9480 and 0.9440, respectively. There were founder and bottleneck haplotypes observed in Xinjiang Uyghurs. Xinjiang Uyghurs are more genetically related to Chinese population in genetics than to Caucasians. Moreover, there was genetic diversity between Uyghurs from the southern and northern regions. There was significance in genetic distance between the southern Xinjiang Uyghurs and Chinese population, but not between the northern Xinjiang Uyghurs and Chinese. The European vs. East Asian contribution to the ten regional Uyghur groups varies among the groups and the European contribution to the Uyghur increases from north to south geographically. This study is the first report on DNA polymorphisms of cytochrome B in the Uyghur population. The study also further confirms that there are significant genetic differences among the Uyghurs in different geographical locations.
Publisher: England: BioMed Central Ltd
Language: English
Identifier: ISSN: 1471-2156
EISSN: 1471-2156
DOI: 10.1186/1471-2156-14-100
PMID: 24103151
Source: Geneva Foundation Free Medical Journals at publisher websites
MEDLINE
PubMed Central
ROAD: Directory of Open Access Scholarly Resources
DOAJ Directory of Open Access Journals

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Genetic diversities of cytochrome B in Xinjiang Uyghur unveiled its origin and migration history

Searching Remote Databases, Please Wait