Language:

World Incidence of AKI: A Meta-Analysis

Clinical journal of the American Society of Nephrology, 2013-09, Vol.8 (9), p.1482-1493 [Peer Reviewed Journal]

Copyright © 2013 by the American Society of Nephrology 2013 ;ISSN: 1555-9041 ;EISSN: 1555-905X ;DOI: 10.2215/CJN.00710113 ;PMID: 23744003

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
World Incidence of AKI: A Meta-Analysis
Author: Susantitaphong, Paweena ; Cruz, Dinna N ; Cerda, Jorge ; Abulfaraj, Maher ; Alqahtani, Fahad ; Koulouridis, Ioannis ; Jaber, Bertrand L
Subjects: Acute Kidney Injury - economics ; Acute Kidney Injury - epidemiology ; Acute Kidney Injury - mortality ; Adult ; Africa, Northern - epidemiology ; Africa, Western - epidemiology ; Asia - epidemiology ; Australia - epidemiology ; Child ; Developed Countries - economics ; Developing Countries - economics ; Europe - epidemiology ; Global Health ; Health Expenditures ; Humans ; Incidence ; New Zealand - epidemiology ; North America - epidemiology ; Original ; Severity of Illness Index ; South America - epidemiology
Is Part Of: Clinical journal of the American Society of Nephrology, 2013-09, Vol.8 (9), p.1482-1493
Description: The burden of AKI around the globe has not been systematically examined. A systematic review (2004-2012) of large cohort studies was conducted to estimate the world incidence of AKI and its stages of severity and associated mortality, and to describe geographic variations according to countries, regions, and their economies. AKI definitions were reclassified according to the Kidney Disease Improving Global Outcomes (KDIGO) staging system. Random-effects model meta-analyses and meta-regressions were used to generate summary estimates and explore sources of heterogeneity. There were 312 studies identified (n=49,147,878) , primarily in hospital settings. Most studies originated from North America, Northern Europe, and Eastern Asia, from high-income countries, and from nations that spent ≥5% of the gross domestic product on total health expenditure. Among the 154 studies (n=3,585,911) that adopted a KDIGO-equivalent AKI definition, the pooled incidence rates of AKI were 21.6% in adults (95% confidence interval [95% CI], 19.3 to 24.1) and 33.7% in children (95% CI, 26.9 to 41.3). The pooled AKI-associated mortality rates were 23.9% in adults (95% CI, 22.1 to 25.7) and 13.8% in children (95% CI, 8.8 to 21.0). The AKI-associated mortality rate declined over time, and was inversely related to income of countries and percentage of gross domestic product spent on total health expenditure. Using the KDIGO definition, 1 in 5 adults and 1 in 3 children worldwide experience AKI during a hospital episode of care. This analysis provides a platform to raise awareness of AKI with the public, government officials, and health care professionals.
Publisher: United States: American Society of Nephrology
Language: English
Identifier: ISSN: 1555-9041
EISSN: 1555-905X
DOI: 10.2215/CJN.00710113
PMID: 23744003
Source: Geneva Foundation Free Medical Journals at publisher websites
MEDLINE
PubMed Central
Alma/SFX Local Collection

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

World Incidence of AKI: A Meta-Analysis

Copyright © 2013 by the American Society of Nephrology 2013 ;ISSN: 1555-9041 ;EISSN: 1555-905X ;DOI: 10.2215/CJN.00710113 ;PMID: 23744003

Searching Remote Databases, Please Wait