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Measures of Cortical Grey Matter Structure and Development in Children with Autism Spectrum Disorder

Journal of autism and developmental disorders, 2012-03, Vol.42 (3), p.419-427 [Peer Reviewed Journal]

Springer Science+Business Media, LLC 2011 ;2015 INIST-CNRS ;COPYRIGHT 2012 Springer ;Springer Science+Business Media, LLC 2012 ;ISSN: 0162-3257 ;EISSN: 1573-3432 ;DOI: 10.1007/s10803-011-1261-6 ;PMID: 21556969 ;CODEN: JADDDQ

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Title:
Measures of Cortical Grey Matter Structure and Development in Children with Autism Spectrum Disorder
Author: Mak-Fan, Kathleen M. ; Taylor, Margot J. ; Roberts, Wendy ; Lerch, Jason P.
Subjects: Adolescent ; Adolescents ; Age ; Age Differences ; Autism ; Autistic children ; Autistic spectrum disorders ; Behavioral Science and Psychology ; Biological and medical sciences ; Brain ; Brain Hemisphere Functions ; Cerebral Cortex - growth & development ; Cerebral Cortex - pathology ; Child ; Child and School Psychology ; Child clinical studies ; Child Development ; Child Development Disorders, Pervasive - pathology ; Children ; Cortex ; Cortex (frontal) ; Cortex (parietal) ; Data processing ; Developmental disorders ; frontal gyrus ; Humans ; Infantile autism ; Male ; Medical sciences ; Nerve Fibers, Unmyelinated - pathology ; Neurodevelopmental disorders ; Neurological Impairments ; Neurosciences ; Organ Size ; Original Paper ; Pediatrics ; Pervasive Developmental Disorders ; Psychology ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Public Health ; Substantia grisea ; Surface area
Is Part Of: Journal of autism and developmental disorders, 2012-03, Vol.42 (3), p.419-427
Description: The current study examined group differences in cortical volume, surface area, and thickness with age, in a group of typically developing children and a group of children with ASD aged 6–15 years. Results showed evidence of age by group interactions, suggesting atypicalities in the relation between these measures and age in the ASD group. Additional vertex-based analyses of cortical thickness revealed that specific regions in the left inferior frontal gyrus (BA 44) and left precuneus showed thicker cortex for the ASD group at younger ages only. These data support the hypothesis of an abnormal developmental trajectory of the cortex in ASD, which could have profound effects on other aspects of neural development in children with ASD.
Publisher: Boston: Springer US
Language: English
Identifier: ISSN: 0162-3257
EISSN: 1573-3432
DOI: 10.1007/s10803-011-1261-6
PMID: 21556969
CODEN: JADDDQ
Source: ProQuest One Psychology
Education Resources Information Center (ERIC)
MEDLINE
Alma/SFX Local Collection
ProQuest Central

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Measures of Cortical Grey Matter Structure and Development in Children with Autism Spectrum Disorder

Springer Science+Business Media, LLC 2011 ;2015 INIST-CNRS ;COPYRIGHT 2012 Springer ;Springer Science+Business Media, LLC 2012 ;ISSN: 0162-3257 ;EISSN: 1573-3432 ;DOI: 10.1007/s10803-011-1261-6 ;PMID: 21556969 ;CODEN: JADDDQ

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