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Immunology of hepatitis B virus and hepatitis C virus infection

Nature reviews. Immunology, 2005-03, Vol.5 (3), p.215-229 [Peer Reviewed Journal]

COPYRIGHT 2005 Nature Publishing Group ;Copyright Nature Publishing Group Mar 2005 ;Nature Publishing Group 2005. ;ISSN: 1474-1733 ;EISSN: 1474-1741 ;DOI: 10.1038/nri1573 ;PMID: 15738952

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Title:
Immunology of hepatitis B virus and hepatitis C virus infection
Author: Rehermann, Barbara ; Nascimbeni, Michelina
Subjects: Adoptive transfer ; Animals ; Antibodies ; Antigens ; Cirrhosis ; Core protein ; Cytotoxicity ; Disease transmission ; DNA viruses ; Experimental infection ; Flavivirus ; Hepacivirus - genetics ; Hepacivirus - immunology ; Hepadnavirus ; Hepatitis B ; Hepatitis B - etiology ; Hepatitis B - immunology ; Hepatitis B - virology ; Hepatitis B e antigen ; Hepatitis B surface antigen ; Hepatitis B virus ; Hepatitis B virus - genetics ; Hepatitis B virus - immunology ; Hepatitis C ; Hepatitis C - etiology ; Hepatitis C - immunology ; Hepatitis C - virology ; Hepatitis C virus ; Hepatitis, Chronic - immunology ; Hepatitis, Chronic - virology ; Hepatocellular carcinoma ; Hepatocytes ; Host range ; Humans ; Immune clearance ; Immune response (humoral) ; Immunity - immunology ; Immunoglobulin G ; Immunoglobulin M ; Infections ; Interferon ; Liver diseases ; Lymphocytes ; Lymphocytes T ; Models, Immunological ; Patients ; RNA viruses ; Transgenic mice ; Viruses ; γ-Interferon
Is Part Of: Nature reviews. Immunology, 2005-03, Vol.5 (3), p.215-229
Description: More than 500 million people worldwide are persistently infected with the hepatitis B virus (HBV) and/or hepatitis C virus (HCV) and are at risk of developing chronic liver disease, cirrhosis and hepatocellular carcinoma. Despite many common features in the pathogenesis of HBV- and HCV-related liver disease, these viruses markedly differ in their virological properties and in their immune escape and survival strategies. This review assesses recent advances in our understanding of viral hepatitis, contrasts mechanisms of virus-host interaction in acute hepatitis B and hepatitis C, and outlines areas for future studies.
Publisher: England: Nature Publishing Group
Language: English
Identifier: ISSN: 1474-1733
EISSN: 1474-1741
DOI: 10.1038/nri1573
PMID: 15738952
Source: MEDLINE
Alma/SFX Local Collection
ProQuest Central

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Immunology of hepatitis B virus and hepatitis C virus infection

COPYRIGHT 2005 Nature Publishing Group ;Copyright Nature Publishing Group Mar 2005 ;Nature Publishing Group 2005. ;ISSN: 1474-1733 ;EISSN: 1474-1741 ;DOI: 10.1038/nri1573 ;PMID: 15738952

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