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Access to Functionalized Isoquinoline N-Oxides via Sequential Electrophilic Cyclization/Cross-Coupling Reactions

Advanced synthesis & catalysis, 2008-08, Vol.350 (11-12), p.1850-1854 [Peer Reviewed Journal]

Copyright © 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim ;ISSN: 1615-4150 ;EISSN: 1615-4169 ;DOI: 10.1002/adsc.200800301

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  • Title:
    Access to Functionalized Isoquinoline N-Oxides via Sequential Electrophilic Cyclization/Cross-Coupling Reactions
  • Author: Ding, Qiuping ; Wu, Jie
  • Subjects: 2-alkynylbenzaldoximes ; cross-coupling reaction ; electrophilic cyclization ; isoquinoline N-oxides
  • Is Part Of: Advanced synthesis & catalysis, 2008-08, Vol.350 (11-12), p.1850-1854
  • Description: Electrophilic cyclization of 2‐alkynylbenzaldoximes with various electrophiles leads to the formation of 4‐iodoisoquinoline N‐oxides or 4‐bromoisoquinoline N‐oxides under mild conditions. The reaction can be transferred to highly functionalized isoquinoline N‐oxides via palladium‐catalyzed cross‐coupling reactions.
  • Publisher: Weinheim: WILEY-VCH Verlag
  • Language: English
  • Identifier: ISSN: 1615-4150
    EISSN: 1615-4169
    DOI: 10.1002/adsc.200800301
  • Source: Alma/SFX Local Collection
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