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Treatment options for oropharyngeal carcinoma - An umbrella review

Folia medica cracoviensia, 2023-10, Vol.63 (3), p.103-124

ISSN: 0015-5616 ;DOI: 10.24425/fmc.2023.147217 ;PMID: 38310532

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  • Title:
    Treatment options for oropharyngeal carcinoma - An umbrella review
  • Author: Plutecki, Dawid ; Szczepanek, Elżbieta ; Szczepanek, Małgorzata ; Nasser, Ameen ; Hajdyła, Paweł ; Wrona, Andrzej
  • Subjects: Carcinoma, Squamous Cell - therapy ; Humans ; Meta-Analysis as Topic ; Oropharyngeal Neoplasms - pathology ; Oropharyngeal Neoplasms - therapy ; Systematic Reviews as Topic
  • Is Part Of: Folia medica cracoviensia, 2023-10, Vol.63 (3), p.103-124
  • Description: Our umbrella review aimed to summarize and revisit the evidence from all of the meta-analyses and systematic reviews regarding the treatments of oropharyngeal squamous cell carcinoma (OPSCC). Major medical databases such as PubMed, Scopus, Embase, Web of Science, Google Scholar, Cochrane Library, BIOSIS, and EBSCO were searched. The overall search process was conducted in 3 stages. Finally, a total of 28 studies met the inclusion criteria and were included in this study. Out of those 28 meta-analyses, a total of 315 primary studies were screened in order to extract the data and perform the statistical analysis. In total, data from 22,619 patients was analyzed. The main objective of the present umbrella review was to summarize and analyze all of the evidence-based data provided by numerous meta-analyses and systematic reviews regarding the treatment of OPSCC. Our study delivers the most up-to-date and evidence-based results regarding the different therapeutic modalities of this malignancy in one concise review, making it the ultimate tool for physicians treating OPSCC.
  • Publisher: Poland
  • Language: English;Polish
  • Identifier: ISSN: 0015-5616
    DOI: 10.24425/fmc.2023.147217
    PMID: 38310532
  • Source: MEDLINE
    Alma/SFX Local Collection
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