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Female subfertility

Nature reviews. Disease primers, 2019-01, Vol.5 (1), p.7-7, Article 7 [Peer Reviewed Journal]

2018© Springer Nature Limited 2018 ;ISSN: 2056-676X ;EISSN: 2056-676X ;DOI: 10.1038/s41572-018-0058-8 ;PMID: 30679436

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Title:
Female subfertility
Author: Farquhar, Cynthia M ; Bhattacharya, Siladitya ; Repping, Sjoerd ; Mastenbroek, Sebastiaan ; Kamath, Mohan S ; Marjoribanks, Jane ; Boivin, Jacky
Subjects: Adult ; Age ; Age Factors ; Cell adhesion & migration ; Embryos ; Epidemiology ; Female ; Fertility Agents - therapeutic use ; Gynecology ; Humans ; Hysterosalpingography - methods ; Infertility ; Infertility, Female - diagnosis ; Infertility, Female - physiopathology ; Infertility, Female - therapy ; Life sciences ; Mass Screening - methods ; Middle Aged ; Obstetrics ; Pregnancy ; Quality of life ; Reproductive health ; Risk Reduction Behavior ; Sperm ; Womens health
Is Part Of: Nature reviews. Disease primers, 2019-01, Vol.5 (1), p.7-7, Article 7
Description: Subfertility is common and affects one in six couples, half of whom lack an explanation for their delay in conceiving. Developments in the diagnosis and treatment of subfertility over the past 50 years have been truly remarkable. Indeed, current generations of couples with subfertility are more fortunate than previous generations, as they have many more opportunities to become parents. The timely access to effective treatment for subfertility is important as many couples have a narrow window of opportunity before the age-related effects of subfertility limit the likelihood of success. Assisted reproduction can overcome the barriers to fertility caused by tubal disease and low sperm count, but little progress has been made in reducing the effect of increasing age on ovarian function. The next 5-10 years will likely see further increases in birth rates in women with subfertility, a greater awareness of lifestyle factors and a possible refinement of current assisted reproduction techniques and the development of new ones. Such progress will bring challenging questions regarding the potential benefits and harms of treatments involving germ cell manipulation, artificial gametes, genetic screening of embryos and gene editing of embryos. We hope to see a major increase in fertility awareness, access to safe and cost-effective fertility care in low-income countries and a reduction in the current disparity of access to fertility care.
Publisher: England: Nature Publishing Group
Language: English
Identifier: ISSN: 2056-676X
EISSN: 2056-676X
DOI: 10.1038/s41572-018-0058-8
PMID: 30679436
Source: MEDLINE
ProQuest Central

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Female subfertility

2018© Springer Nature Limited 2018 ;ISSN: 2056-676X ;EISSN: 2056-676X ;DOI: 10.1038/s41572-018-0058-8 ;PMID: 30679436

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