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Acute Graft-versus-Host Disease — Biologic Process, Prevention, and Therapy

The New England journal of medicine, 2017-11, Vol.377 (22), p.2167-2179 [Peer Reviewed Journal]

Copyright © 2017 Massachusetts Medical Society. All rights reserved. ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMra1609337 ;PMID: 29171820

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Title:
Acute Graft-versus-Host Disease — Biologic Process, Prevention, and Therapy
Author: Zeiser, Robert ; Blazar, Bruce R
Longo, Dan L ; Longo, Dan L.
Subjects: Acute Disease ; Adenosine ; Animals ; Antigens ; Blood diseases ; Bone marrow ; Care and treatment ; Cyclin-dependent kinases ; Cytokines ; Dendritic cells ; Disease Models, Animal ; Gastrointestinal tract ; Glucocorticoids - therapeutic use ; Graft versus host disease ; Graft versus host reaction ; Graft vs Host Disease - immunology ; Graft vs Host Disease - pathology ; Graft vs Host Disease - prevention & control ; Graft vs Host Disease - therapy ; Growth factors ; Hematopoietic Stem Cell Transplantation - adverse effects ; Hematopoietic stem cells ; Humans ; Immunology ; Immunosuppression ; Immunosuppressive agents ; Kinases ; Leukemia ; Lymphatic system ; Lymphocytes ; Lymphocytes T ; Mice ; Neutrophils ; Prevention ; Proteins ; Risk factors ; Stem cell transplantation ; T-Lymphocytes - physiology ; Transplantation ; Transplantation Immunology ; Transplantation, Homologous ; Transplants & implants ; Tumor necrosis factor-TNF
Is Part Of: The New England journal of medicine, 2017-11, Vol.377 (22), p.2167-2179
Description: When T cells from a bone marrow donor begin to attack the host within 3 months after hematopoietic-cell transplantation, acute graft-versus-host disease results. The disease mainly affects the skin, liver, and gastrointestinal tract and is treated with immunosuppressive drugs.
Publisher: United States: Massachusetts Medical Society
Language: English
Identifier: ISSN: 0028-4793
EISSN: 1533-4406
DOI: 10.1056/NEJMra1609337
PMID: 29171820
Source: ProQuest One Psychology
MEDLINE
ProQuest Central

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Acute Graft-versus-Host Disease — Biologic Process, Prevention, and Therapy

Copyright © 2017 Massachusetts Medical Society. All rights reserved. ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMra1609337 ;PMID: 29171820

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