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The microbiome and innate immunity

Nature (London), 2016-07, Vol.535 (7610), p.65-74 [Peer Reviewed Journal]

COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Jul 7, 2016 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature18847 ;PMID: 27383981 ;CODEN: NATUAS

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Title:
The microbiome and innate immunity
Author: Thaiss, Christoph A ; Zmora, Niv ; Levy, Maayan ; Elinav, Eran
Subjects: Animals ; Autoimmunity ; Bacteria ; Digestive system ; Epigenesis, Genetic ; Gastrointestinal Microbiome - immunology ; Gastrointestinal Microbiome - physiology ; Homeostasis ; Host-parasite relationships ; Humans ; Immune response ; Immune system ; Immunity, Innate - genetics ; Immunity, Innate - immunology ; Immunity, Innate - physiology ; Infection - genetics ; Infection - immunology ; Infection - microbiology ; Inflammation - genetics ; Inflammation - microbiology ; Inflammation - pathology ; Intestinal Mucosa - cytology ; Intestinal Mucosa - microbiology ; Intestinal Mucosa - physiology ; Kinases ; Lymphocytes - physiology ; Metabolic Syndrome - metabolism ; Metabolic Syndrome - microbiology ; Metabolic Syndrome - pathology ; Metabolism ; Metabolites ; Microorganisms ; Myeloid Cells - physiology ; Neoplasms - genetics ; Neoplasms - microbiology ; Neoplasms - pathology ; Observations ; Proteins ; Signal transduction
Is Part Of: Nature (London), 2016-07, Vol.535 (7610), p.65-74
Description: The intestinal microbiome is a signalling hub that integrates environmental inputs, such as diet, with genetic and immune signals to affect the host's metabolism, immunity and response to infection. The haematopoietic and non-haematopoietic cells of the innate immune system are located strategically at the host-microbiome interface. These cells have the ability to sense microorganisms or their metabolic products and to translate the signals into host physiological responses and the regulation of microbial ecology. Aberrations in the communication between the innate immune system and the gut microbiota might contribute to complex diseases.
Publisher: England: Nature Publishing Group
Language: English
Identifier: ISSN: 0028-0836
EISSN: 1476-4687
DOI: 10.1038/nature18847
PMID: 27383981
CODEN: NATUAS
Source: ProQuest One Psychology
MEDLINE
ProQuest Central

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The microbiome and innate immunity

COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Jul 7, 2016 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature18847 ;PMID: 27383981 ;CODEN: NATUAS

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