Language:

Economic analysis comparing induction of labor and expectant management in women with preterm prelabor rupture of membranes between 34 and 37 weeks (PPROMEXIL trial)

Acta obstetricia et gynecologica Scandinavica, 2014-04, Vol.93 (4), p.374-381 [Peer Reviewed Journal]

2014 Nordic Federation of Societies of Obstetrics and Gynecology ;2014 Nordic Federation of Societies of Obstetrics and Gynecology. ;ISSN: 0001-6349 ;EISSN: 1600-0412 ;DOI: 10.1111/aogs.12329 ;PMID: 24392746 ;CODEN: AOGSAE

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Economic analysis comparing induction of labor and expectant management in women with preterm prelabor rupture of membranes between 34 and 37 weeks (PPROMEXIL trial)
Author: Vijgen, Sylvia M. C. ; van der Ham, David P. ; Bijlenga, Denise ; van Beek, Johannes J. ; Bloemenkamp, Kitty W. M. ; Kwee, Anneke ; Groenewout, Mariët ; Kars, Michael M. ; Kuppens, Simone ; Mantel, Gerald ; Molkenboer, Jan F. M. ; Mulder, Antonius L. M. ; Nijhuis, Jan G. ; Pernet, Paula J. M. ; Porath, Martina ; Woiski, Mallory D. ; Weinans, Martin J. N. ; van Wijngaarden, Wim J. ; Wildschut, Hajo I. J. ; Akerboom, Bertina ; Sikkema, J. Marko ; Willekes, Christine ; Mol, Ben W. J. ; Opmeer, Brent C.
Subjects: Adult ; Analgesics - administration & dosage ; Analgesics - economics ; Cost Control ; Cost Savings ; Cost-Benefit Analysis ; Costs ; Critical Care - economics ; Delivery, Obstetric - economics ; expectant management ; Female ; Fetal Membranes, Premature Rupture - economics ; Fetal Membranes, Premature Rupture - therapy ; Humans ; Incidence ; induction ; Infant, Newborn ; Intensive Care, Neonatal - economics ; labor ; Labor, Induced - economics ; Labor, Induced - methods ; Length of Stay - economics ; Monitoring, Physiologic - economics ; Netherlands - epidemiology ; PPROM ; Pregnancy ; Pregnancy Trimester, Third ; Sepsis - epidemiology ; Watchful Waiting - economics
Is Part Of: Acta obstetricia et gynecologica Scandinavica, 2014-04, Vol.93 (4), p.374-381
Description: Objective To compare the costs of induction of labor and expectant management in women with preterm prelabor rupture of membranes (PPROM). Design Economic analysis based on a randomized clinical trial. Setting Obstetric departments of eight academic and 52 non‐academic hospitals in the Netherlands. Population Women with PPROM near term who were not in labor 24 h after PPROM. Methods A cost‐minimization analysis was done from a health care provider perspective, using a bottom‐up approach to estimate resource utilization, valued with unit‐costs reflecting actual costs. Main outcome measures Primary health outcome was the incidence of neonatal sepsis. Direct medical costs were estimated from start of randomization to hospital discharge of mother and child. Results Induction of labor did not significantly reduce the probability of neonatal sepsis [2.6% vs. 4.1%, relative risk 0.64 (95% confidence interval 0.25–1.6)]. Mean costs per woman were €8094 for induction and €7340 for expectant management (difference €754; 95% confidence interval −335 to 1802). This difference predominantly originated in the postpartum period, where the mean costs were €5669 for induction vs. €4801 for expectant management. Delivery costs were higher in women allocated to induction than in women allocated to expectant management (€1777 vs. €1153 per woman). Antepartum costs in the expectant management group were higher because of longer antepartum maternal stays in hospital. Conclusions In women with pregnancies complicated by PPROM near term, induction of labor does not reduce neonatal sepsis, whereas costs associated with this strategy are probably higher.
Publisher: United States: Blackwell Publishing Ltd
Language: English;French;German
Identifier: ISSN: 0001-6349
EISSN: 1600-0412
DOI: 10.1111/aogs.12329
PMID: 24392746
CODEN: AOGSAE
Source: Journals@Ovid Open Access Journal Collection Rolling
MEDLINE
Alma/SFX Local Collection

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Economic analysis comparing induction of labor and expectant management in women with preterm prelabor rupture of membranes between 34 and 37 weeks (PPROMEXIL trial)

2014 Nordic Federation of Societies of Obstetrics and Gynecology ;2014 Nordic Federation of Societies of Obstetrics and Gynecology. ;ISSN: 0001-6349 ;EISSN: 1600-0412 ;DOI: 10.1111/aogs.12329 ;PMID: 24392746 ;CODEN: AOGSAE

Searching Remote Databases, Please Wait