skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Search type Index

Acquired C1-inhibitor deficiency in chronic lymphocytic leukaemia: a case report

Hong Kong medical journal = Xianggang yi xue za zhi, 2022-10, Vol.28 (5), p.403 [Peer Reviewed Journal]

2022. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1024-2708 ;EISSN: 2226-8707 ;DOI: 10.12809/hkmj219478 ;PMID: 38232966

Full text available

Citations Cited by
  • Title:
    Acquired C1-inhibitor deficiency in chronic lymphocytic leukaemia: a case report
  • Author: Tang, A S O ; Wong, Q Y ; Yeo, S T ; Lee, J T H ; Leong, T S ; Chew, L P
  • Subjects: Antigens ; Biopsy ; Case reports ; Chemotherapy ; Edema ; Family medical history ; Hematology ; Hospitals ; Humans ; Internal medicine ; Leukemia ; Leukemia, Lymphocytic, Chronic, B-Cell - complications ; Medical screening ; Medicine ; Patients ; Urticaria
  • Is Part Of: Hong Kong medical journal = Xianggang yi xue za zhi, 2022-10, Vol.28 (5), p.403
  • Description: The patient screened seronegative for human immunodeficiency virus, syphilis, and hepatitis B and C. Overall findings were consistent with a diagnosis of CLL Rai stage II (Binet stage B), with Eastern Cooperative Oncology Group performance status zero. To the best of our knowledge, only about 20 cases of CLL have been reported to be associated with angio-oedema.2 Many diseases are reported to be associated with acquired angio-oedema, with lymphoproliferative disorders and B-cell malignancies the most common.3 In acquired angio-oedema, C1 esterase inhibitor protein level is decreased due to excessive consumption, or may be dysfunctional due to the presence of antibodies against C1 inhibitor, leading to defective inhibition of the complements and kinin system. Long-term prophylactic treatment with antifibrinolytic agents and danazol has been shown to be equally efficacious,2 with a recommendation to avoid the former in the presence of thromboembolic risk factors.2 It is vital to treat the underlying disease to prevent acute attacks, regardless of the treatment options.2 Our patient has had no further attacks of angio-oedema after receiving rituximab, cyclophosphamide, vincristine, and prednisolone chemotherapy.
  • Publisher: China: Hong Kong Academy of Medicine
  • Language: English;Chinese
  • Identifier: ISSN: 1024-2708
    EISSN: 2226-8707
    DOI: 10.12809/hkmj219478
    PMID: 38232966
  • Source: Geneva Foundation Free Medical Journals at publisher websites
    MEDLINE
    ProQuest Central
    DOAJ Directory of Open Access Journals
Back to results list
INSPIRE LIBRARY - TON DUC THANG UNIVERSITY (84-028) 37 755 057 Feedback
19 Nguyen Huu Tho St. Dist.7, HCM thuvien@tdtu.edu.vn

Copyright © 2017 INSPIRE LIBRARY - TON DUC THANG UNIVERSITY

Searching Remote Databases, Please Wait