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Renin–Angiotensin System Inhibition in Advanced Chronic Kidney Disease

The New England journal of medicine, 2022-12, Vol.387 (22), p.2021-2032 [Peer Reviewed Journal]

Copyright © 2022 Massachusetts Medical Society. All rights reserved. ;Copyright © 2022 Massachusetts Medical Society. ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa2210639 ;PMID: 36326117

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Title:
Renin–Angiotensin System Inhibition in Advanced Chronic Kidney Disease
Author: Bhandari, Sunil ; Mehta, Samir ; Khwaja, Arif ; Cleland, John G.F. ; Ives, Natalie ; Brettell, Elizabeth ; Chadburn, Marie ; Cockwell, Paul
Subjects: Angiotensin Receptor Antagonists - adverse effects ; Angiotensin Receptor Antagonists - pharmacology ; Angiotensin Receptor Antagonists - therapeutic use ; Angiotensin-converting enzyme inhibitors ; Angiotensin-Converting Enzyme Inhibitors - adverse effects ; Angiotensin-Converting Enzyme Inhibitors - pharmacology ; Angiotensin-Converting Enzyme Inhibitors - therapeutic use ; Angiotensins - pharmacology ; Antihypertensive Agents - adverse effects ; Antihypertensive Agents - pharmacology ; Antihypertensive Agents - therapeutic use ; Antihypertensives ; Blood pressure ; Cardiology ; Cardiology General ; Clinical Medicine ; Clinical Medicine General ; Confidence intervals ; Creatinine ; Developmental stages ; Diabetes mellitus ; End-stage renal disease ; Epidermal growth factor receptors ; Glomerular Filtration Rate ; Hemodialysis ; Humans ; Hypertension ; Hypothesis testing ; Kidney diseases ; Kidney Failure, Chronic - complications ; Kidney Failure, Chronic - drug therapy ; Kidney transplants ; Kidneys ; Medical research ; Nephrology ; Nephrology General ; Patient safety ; Patients ; Proteins ; Proteinuria ; Quality of Life ; Renal Insufficiency, Chronic - complications ; Renal Insufficiency, Chronic - drug therapy ; Renin ; Renin-Angiotensin System - drug effects ; Statistical analysis ; Variables
Is Part Of: The New England journal of medicine, 2022-12, Vol.387 (22), p.2021-2032
Description: In this randomized trial, the discontinuation of renin–angiotensin system inhibitors in patients with advanced chronic kidney disease did not lead to a significant between-group difference in the long-term rate of decline in the eGFR.
Publisher: United States: Massachusetts Medical Society
Language: English
Identifier: ISSN: 0028-4793
EISSN: 1533-4406
DOI: 10.1056/NEJMoa2210639
PMID: 36326117
Source: ProQuest One Psychology
MEDLINE
ProQuest Central

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Renin–Angiotensin System Inhibition in Advanced Chronic Kidney Disease

Copyright © 2022 Massachusetts Medical Society. All rights reserved. ;Copyright © 2022 Massachusetts Medical Society. ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa2210639 ;PMID: 36326117

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