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OCT, OCTA show promise in screening for DR

Optometry times, 2020-06, Vol.12 (6), p.1-33

Copyright MultiMedia Healthcare Inc. Jun 2020 ;ISSN: 0890-7080 ;EISSN: 2328-3904

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  • Title:
    OCT, OCTA show promise in screening for DR
  • Author: Dorgeloh, Kyra ; Zhu, Lucy ; Mehta, Nitish ; Wong, Thomas A
  • Subjects: Algorithms ; Diabetes ; Diabetic retinopathy ; Edema ; Fractals ; Ischemia ; Medical imaging ; Morphology ; Pathology ; Retina ; Telemedicine
  • Is Part Of: Optometry times, 2020-06, Vol.12 (6), p.1-33
  • Description: RETINA This imaging technique provides depth-resolved images of retinal vasculature As COVID-19 changes practice operations, telehealth is on the rise as a viable option for patients who may not obtain in-person eye care.1 Currently, video and telephone-based consultations are garnishing the most attention; however, telemedicine has been making waves in eye care for the past several years, particularly when it comes to the retina. Neural networks have demonstrated high levels of sensitivity and specificity in the detection of referral-warranted DR from single-field fundus photographs.3 The application of these algorithms in the management of DR represent opportunities to broadly screen the general population to greater identify disease.4 Other retinal imaging technologies have been suggested as prime platforms for screening, particularly optical coherence tomography (OCT) and OCT angiography (OCTA). Transit time and dynamic dye changes (leakage, pooling, staining) can be used in order to distinguish among ocular pathologies.6 However, leakage can obscure underlying structure detail from view.7 Additionally, FA is limited to a 2-dimensional view of all retinal vascularization; the depth of an abnormality cannot be examined. OCTA can identify and quantify enlargement of the foveal avascular zone, areas of capillary dropout, and an overall decrease in density of the parafoveal vessels in a non-invasive manner and may prove to be a reliable indicator of DMI.16 It is important to remember that diabetic mac- ular ischemia predicts retinopathy progression (research to date shows that patients with NPDR, DMI, and DME may progress to PDR despite monthly anti-vascular endothelial growth factor (VEGF) treatment.17 Additionally, the more ischemic the macula, the worse the visual prognosis.
  • Publisher: Monmouth Junction: MultiMedia Healthcare Inc
  • Language: English
  • Identifier: ISSN: 0890-7080
    EISSN: 2328-3904
  • Source: ProQuest Central
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