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Vaginal delivery in SARS‐CoV‐2 infected pregnant women in Northern Italy: a retrospective analysis

BJOG: An International Journal of Obstetrics & Gynaecology, 2020-08 [Peer Reviewed Journal]

2020. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the associated terms available at https://novel-coronavirus.onlinelibrary.wiley.com ;DOI: 10.1111/1471-0528.16278

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  • Title:
    Vaginal delivery in SARS‐CoV‐2 infected pregnant women in Northern Italy: a retrospective analysis
  • Author: Ferrazzi, Enrico ; Frigerio, Luigi ; Savasi, Valeria ; Vergani, Patrizia ; Prefumo, Federico ; Barresi, Santa ; Bianchi, Stefano ; Ciriello, Elena ; Facchinetti, Fabio ; Gervasi, Maria Teresa ; Iurlaro, Enrico ; Kustermann, Alessandra ; Mangili, Giovanna ; Mosca, Fabio ; Patanè, Luisa ; Spazzini, Donata ; Spinillo, Arsenio ; Trojano, Giuseppe ; Vignali, Michele ; Villa, Antonella ; Zuccotti, GianVincenzo ; Parazzini, Fabio ; Cetin, Irene
  • Is Part Of: BJOG: An International Journal of Obstetrics & Gynaecology, 2020-08
  • Description: Objective To report mode of delivery and immediate neonatal outcome in COVID‐19 infected women. Design This is a retrospective study. Setting Twelve hospitals in northern Italy. Participants Pregnant women with COVID‐19 confirmed infection who delivered. Exposure COVID 19 infection in pregnancy. Methods SARS‐CoV‐2 infected women who were admitted and delivered during the period 1‐20 march 2020 were eligible. Data were collected from the clinical records using a standardized questionnaire on maternal general characteristics, any medical or obstetric co‐morbidity, course of pregnancy, clinical signs and symptoms, treatment of COVID 19 infection, mode of delivery, neonatal data and breastfeeding Main Outcome and Measure Data on mode of delivery and neonatal outcome Results 42 women with COVID‐19 delivered at the participating centres: 24(57,1%, 95% CI= 41,0‐72,3) delivered vaginally. An elective cesarean section was performed in 18/42 (42,9%, 95%CI 27,7‐59,0) cases: in 8 cases the indication was unrelated to COVID‐19 infection. Pneumonia was diagnosed in 19/42(45,2%, 95%CI 29,8‐61,3) cases: of these 7/19(36,8%,95CI 16,3‐61,6) required oxygen support and 4/19(21,1%,95%CI=6,1‐45,6) were admitted to a critical care unit. Two women with COVID‐19 breastfed without a mask because infection was diagnosed in the post‐partum period: their new‐borns tested positive for SARS‐Cov‐2 infection. In one case a new‐born had a positive test after a vaginal operative delivery. Conclusions Although post‐partum infection cannot be excluded with 100% certainty, these findings suggest that vaginal delivery is associated with a low risk of intrapartum SARS‐Cov‐2 transmission to the new‐born.
  • Publisher: Hoboken: John Wiley & Sons, Inc
  • Language: English
  • Identifier: DOI: 10.1111/1471-0528.16278
  • Source: Coronavirus Research Database
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