skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Search type Index

AB1075 Relationship of serum cholecalciferol (VITAMIN D3) level with musculoskeletal symptoms

Annals of the rheumatic diseases, 2018-06, Vol.77 (Suppl 2), p.1647 [Peer Reviewed Journal]

2018, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions ;Copyright: 2018 © 2018, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions ;ISSN: 0003-4967 ;EISSN: 1468-2060 ;DOI: 10.1136/annrheumdis-2018-eular.6070

Full text available

Citations Cited by
  • Title:
    AB1075 Relationship of serum cholecalciferol (VITAMIN D3) level with musculoskeletal symptoms
  • Author: Razzaque, M.A. ; Dewan, G. ; biswas, R.S. ; karim, M.N. ; sultan, I.
  • Subjects: Body mass index ; Chronic fatigue syndrome ; Fatigue ; Fibromyalgia ; Myalgia ; Nutrient deficiency ; Pain ; Patients ; Skin ; Statistical analysis ; Sunlight ; Vitamin D ; Vitamin D3 ; Vitamin deficiency
  • Is Part Of: Annals of the rheumatic diseases, 2018-06, Vol.77 (Suppl 2), p.1647
  • Description: BackgroundPatients suffering from generalised aches and pains, not adequately responding to treatment are usually considered as fibromyalgia, depression, chronic fatigue syndrome etc. But those patients need further evaluation and low vitamin D is often the underlying cause. Both clinical and subclinical low level vitamin D is common.1 ObjectivesTo assess the relationship between musculoskeletal complaints and serum vitamin D3(cholecalciferol) level.MethodsThis prospective cross-sectional descriptive study was conducted during July 2017 to December 2017 in Chittagong, Bangladesh. Patients with common musculoskeletal complaints were enrolled. Each patient was screened to exclude common possibilities. Serum cholecalciferol was measured for each patient. Race, occupation, skin complexion, body mass index, sunlight exposure, covering of body with clothing’s and use of sunscreen were taken under consideration in final analysis. Visual analogue scale (VAS; 1–10) was used to quantify all complaints. Correlation of serum cholecalciferol level with VAS score of individual complaints was analysed.ResultsA total of 110 patients (79 Female and 31 Male) were enrolled after screening 165. All of them were Bangladeshi of multi-ethnic Asian origin. Mean age was 46.5±12.8 years. Their skin complexions were pale white to white skin 45.5%, light brown 30%, moderate brown 11.8% and dark brown 12.7%. Most had (90.9%; n=100) inadequate sunlight exposure and 77.2% (n=61) women used Burkah (full covered dress). Mean vitamin D3 level was 25.2±7.3 ng/ml. Vitamin D deficiency was (mean 17.3±2.8 ng/ml) observed in 30 (27.3%), insufficiency (mean 25.1±2.7 ng/ml) in 62 (56.4%) and normal level (mean 34.8±4.4 ng/ml) in 18 (16.4%). After classifying Vitamin D level in relation to symptoms it was found that majority of patients (81.2% to 90.3%; depending on complaints) had insufficient or deficient cholecalciferol level (table 1).Abstract AB1075 – Table 1Serum cholecalciferol status in different musculoskeletal complaintsComplaints Vit D3Normal(≥30 ng/ml)Insufficiency(20-<30 ng/ml)Deficiency(<20 ng/ml) n%n%n% Myalgia (n=104; 94.5%)1615.46057.72826.9Muscle cramp (n=104; 94.5%)1817.36057.72625.0Generalised weakness (n=99; 90.0%)1818.25656.52525.2Difficulty in climbing stairs (n=89;80.9%)1415.75056.22528.1Fatigue (n=87; 79.1%)138.15158.62326.4Difficulty in squatting (n=84; 76.4%)910.74958.32630.9Pain in weight bearing joints (n=80; 72.7%)113.74961.22025.0Bone pain (n=73; 66.4%)810.94358.92230.1Significant negative correlation was found between the serum cholecalciferol level and VAS for difficulty in getting up from squatting position (r=−0.253, p=0.008) and positive correlation was found for muscle cramps (r=0.220, p=0.021). Correlations with remaining symptoms were not statistically significant.ConclusionsVitamin D status directly and indirectly influences musculoskeletal health. Hypovitaminosis D should consider in every patient with muscle cramp.Reference[1] Jones AN, Hansen KE. Recognizing the musculoskeletal manifestations of vitamin D deficiency. J Musculoskelet Med. 2009; 26(10): 389 – 96.AcknowledgementsHafsa habiba, Rayhana BegumDisclosure of InterestM. A. Razzaque Consultant for: research, G. Dewan Consultant for: research, R. biswas Consultant for: research, M. karim Consultant for: research, I. sultan Consultant for: research
  • Publisher: London: BMJ Publishing Group LTD
  • Language: English
  • Identifier: ISSN: 0003-4967
    EISSN: 1468-2060
    DOI: 10.1136/annrheumdis-2018-eular.6070
  • Source: ProQuest Central
Back to results list
INSPIRE LIBRARY - TON DUC THANG UNIVERSITY (84-028) 37 755 057 Feedback
19 Nguyen Huu Tho St. Dist.7, HCM thuvien@tdtu.edu.vn

Copyright © 2017 INSPIRE LIBRARY - TON DUC THANG UNIVERSITY

Searching Remote Databases, Please Wait