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Reproducible Research Practices and Transparency across the Biomedical Literature

PLoS biology, 2016-01, Vol.14 (1), p.e1002333-e1002333 [Peer Reviewed Journal]

2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Iqbal SA, Wallach JD, Khoury MJ, Schully SD, Ioannidis JPA (2016) Reproducible Research Practices and Transparency across the Biomedical Literature. PLoS Biol 14(1): e1002333. doi:10.1371/journal.pbio.1002333 ;ISSN: 1545-7885 ;ISSN: 1544-9173 ;EISSN: 1545-7885 ;DOI: 10.1371/journal.pbio.1002333 ;PMID: 26726926

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  • Title:
    Reproducible Research Practices and Transparency across the Biomedical Literature
  • Author: Iqbal, Shareen A ; Wallach, Joshua D ; Khoury, Muin J ; Schully, Sheri D ; Ioannidis, John P A
  • Vaux, David L
  • Subjects: Biomedical Research - economics ; Biomedical Research - statistics & numerical data ; Clinical medicine ; Clinical trials ; Conflict of Interest ; Data analysis ; Datasets ; Funding ; Meta ; Periodicals as Topic - statistics & numerical data ; Public access ; Reproducibility of Results
  • Is Part Of: PLoS biology, 2016-01, Vol.14 (1), p.e1002333-e1002333
  • Description: There is a growing movement to encourage reproducibility and transparency practices in the scientific community, including public access to raw data and protocols, the conduct of replication studies, systematic integration of evidence in systematic reviews, and the documentation of funding and potential conflicts of interest. In this survey, we assessed the current status of reproducibility and transparency addressing these indicators in a random sample of 441 biomedical journal articles published in 2000-2014. Only one study provided a full protocol and none made all raw data directly available. Replication studies were rare (n = 4), and only 16 studies had their data included in a subsequent systematic review or meta-analysis. The majority of studies did not mention anything about funding or conflicts of interest. The percentage of articles with no statement of conflict decreased substantially between 2000 and 2014 (94.4% in 2000 to 34.6% in 2014); the percentage of articles reporting statements of conflicts (0% in 2000, 15.4% in 2014) or no conflicts (5.6% in 2000, 50.0% in 2014) increased. Articles published in journals in the clinical medicine category versus other fields were almost twice as likely to not include any information on funding and to have private funding. This study provides baseline data to compare future progress in improving these indicators in the scientific literature.
  • Publisher: United States: Public Library of Science
  • Language: English
  • Identifier: ISSN: 1545-7885
    ISSN: 1544-9173
    EISSN: 1545-7885
    DOI: 10.1371/journal.pbio.1002333
    PMID: 26726926
  • Source: Open Access: PubMed Central
    Geneva Foundation Free Medical Journals at publisher websites
    AUTh Library subscriptions: ProQuest Central
    PLoS
    MEDLINE
    DOAJ Directory of Open Access Journals

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