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Early-Onset Myasthenia Gravis Following COVID-19 Vaccination

Journal of Korean Medical Science, 2022, 37(10), , pp.1-4 [Peer Reviewed Journal]

COPYRIGHT(C) KYOBO BOOK CENTRE ALL RIGHTS RESERVED ;2022 The Korean Academy of Medical Sciences. ;2022 The Korean Academy of Medical Sciences. 2022 The Korean Academy of Medical Sciences ;ISSN: 1011-8934 ;EISSN: 1598-6357 ;DOI: 10.3346/jkms.2022.37.e50 ;PMID: 35289135

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  • Title:
    Early-Onset Myasthenia Gravis Following COVID-19 Vaccination
  • Author: Lee Myung Ah ; Lee Chonghwee ; Park Jung Hyun ; 이정환
  • Subjects: Adult ; BNT162 Vaccine - adverse effects ; Case Report ; Electromyography ; Female ; Humans ; Myasthenia Gravis - diagnosis ; Myasthenia Gravis - etiology ; Myasthenia Gravis - physiopathology ; Neostigmine - pharmacology ; Republic of Korea ; Time Factors ; 의학일반
  • Is Part Of: Journal of Korean Medical Science, 2022, 37(10), , pp.1-4
  • Description: As coronavirus disease 2019 (COVID-19) has spread worldwide, the rate of COVID-19 vaccination uptake is encouraging. Neurological complications associated with COVID-19 vaccines such as stroke, Guillain-Barré syndrome, and Bell's palsy have been reported. Recently, late-onset myasthenia gravis (MG) following COVID-19 vaccination has been reported. To date, however, there has been no evidence of increased risk of early-onset MG following COVID-19. Here, we report a case of a patient with new-onset MG that arose after receiving a COVID-19 vaccine. A 33-year-old woman suddenly experienced generalized weakness and diplopia on the evening she had received the second dose of the Pfizer-BioNTech COVID-19 vaccine. The temporal relationship suggests that this new-onset MG is related to the vaccination. It also implies that COVID-19 vaccination could trigger early-onset MG symptoms in patients at risk of MG.
  • Publisher: Korea (South): 대한의학회
  • Language: Korean;English
  • Identifier: ISSN: 1011-8934
    EISSN: 1598-6357
    DOI: 10.3346/jkms.2022.37.e50
    PMID: 35289135
  • Source: KoreaMed Synapse
    GFMER Free Medical Journals
    MEDLINE
    PubMed Central
    KoreaMed Open Access
    ROAD: Directory of Open Access Scholarly Resources
    DOAJ Directory of Open Access Journals
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