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Analyzing Population Genetics Using the Mitochondrial Control Region and Bioinformatics

Bioscene (Association of College and University Biology Educators), 2010-05, Vol.36 (1), p.26 [Peer Reviewed Journal]

ISSN: 1539-2422

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  • Title:
    Analyzing Population Genetics Using the Mitochondrial Control Region and Bioinformatics
  • Author: Sato, Takumi ; Phillips, Bonnie ; Latourelle, Sandra M ; Elwess, Nancy L
  • Subjects: Active Learning ; Asians ; Biology ; College Science ; Foreign Students ; Genetics ; Information Science ; Inquiry ; New York ; Research Projects ; Scientific Research ; Student Projects ; Undergraduate Students
  • Is Part Of: Bioscene (Association of College and University Biology Educators), 2010-05, Vol.36 (1), p.26
  • Description: The 14-base pair hypervariable region in mitochondrial DNA (mtDNA) of Asian populations, specifically Japanese and Chinese students at Plattsburgh State University, was examined. Previous research on this 14-base pair region showed it to be susceptible to mutations and as a result indicated direct correlation with specific ethnic populations. Earlier studies provided the 14-base pair region sequence analysis for Asians in general. This inquiry-based project was generated in a junior/senior college general genetics course. The project produced sequences of the 14-base pair hypervariable region for Japanese and Chinese populations, specifically. The investigation examined 28 Japanese and 27 Chinese international students. A Control group, consisting of 20 random students was also sampled. The 14-base pair hypervariable region for each sample was analyzed through comparison using bioinformatics. Analyzing the samples showed that, overall, 46% of the Japanese samples, 59% of the Chinese samples, and 75% of the Control samples had the same 14-base pair sequence. In addition to this, it was observed that the Japanese, Chinese, and Control group all had their own specific mutations within the 14-base pair hypervariable region. (Contains 3 figures and 2 tables.)
  • Publisher: Association of College and Biology Educators
  • Language: English
  • Identifier: ISSN: 1539-2422
  • Source: ERIC Full Text Only (Discovery)
    Alma/SFX Local Collection
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