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Prognostic diagnosis marker Claudin 22 of ovarian cancer and application of prognostic diagnosis marker Claudin 22
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Title:
Prognostic diagnosis marker Claudin 22 of ovarian cancer and application of prognostic diagnosis marker Claudin 22
Author:
YANG YUE
;
SHI LIANG
;
HUANG PING
;
LU CHAO
;
FU ZHIQIN
;
YU TINGTING
;
ZHOU CHENXI
Subjects:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
;
MEASURING
;
PHYSICS
;
TESTING
Description:
The invention relates to a prognosis marker Claudin 22 of ovarian cancer and application thereof, and firstly finds that the expression quantity of the ovarian cancer drug-resistant marker Claudin 22is related to the prognosis of ovarian cancer, specifically, in prognosis indexes such as no progression lifetime and total lifetime when Claudin 22 is highly expressed, ovarian cancer cases show poorprognosis, and prognosis accuracy is high. The discovery of the prognosis marker Claudin 22 provides prognosis prompts for clinical treatment of ovarian cancer, including chemotherapy and surgical treatment. 本发明为一种卵巢癌的预后诊断标志物Claudin22及其应用,首次发现卵巢癌耐药标志物Claudin22的表达量卵巢癌的预后相关,具体为当Claudin22高表达时无进展生存期、总生存期中等预后指标中,卵巢癌病例表现为不良预后,即本发明的发现为卵巢癌的临床治疗中包括化疗、手术治疗提供预后提示。
Creation Date:
2021
Language:
Chinese;English
Source:
esp@cenet
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