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Carbohydrate antigen 125 predicts pulmonary congestion in patients with ST-segment elevation myocardial infarction

Brazilian journal of medical and biological research, 2019-01, Vol.52 (12), p.e9124-e9124 [Tạp chí có phản biện]

COPYRIGHT 2019 Associacao Brasileira de Divulgacao Cientifica (ABDC) ;COPYRIGHT 2019 Associacao Brasileira de Divulgacao Cientifica (ABDC) ;Copyright Revista Brasileira de Pesquisas Medicas 2019 ;This work is licensed under a Creative Commons Attribution 4.0 International License. ;ISSN: 0100-879X ;ISSN: 1414-431X ;EISSN: 1414-431X ;DOI: 10.1590/1414-431X20199124 ;PMID: 31826182

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Nhan đề:
Carbohydrate antigen 125 predicts pulmonary congestion in patients with ST-segment elevation myocardial infarction
Tác giả: Falcão, F J A ; Oliveira, F R A ; Cantarelli, F ; Cantarelli, R ; Brito-Júnior, P ; Lemos, H ; Silva, P ; Camboim, I ; Freire, M C ; Carvalho, O ; Sobral-Filho, D C
Chủ đề: Acute coronary syndrome ; Aged ; Angioplasty ; Antigens ; Balloon angioplasty ; BIOLOGY ; Biomarkers ; Biomarkers - blood ; Brain natriuretic peptide ; CA-125 Antigen - blood ; CA125 antigen ; Cardiovascular diseases ; Congestive heart failure ; Coronary artery disease ; Coronary heart disease ; Cross-Sectional Studies ; Diseases ; Edema ; Electrocardiography ; Female ; Heart attack ; Heart attacks ; Heart diseases ; Heart failure ; Humans ; Inflammation ; Male ; Medical research ; Medicine, Experimental ; MEDICINE, RESEARCH & EXPERIMENTAL ; Middle Aged ; Myocardial infarction ; Natriuretic peptides ; Natriuretric peptide ; Ovarian cancer ; Peptides ; Predictive Value of Tests ; Prognosis ; Pulmonary edema ; Pulmonary Edema - blood ; Pulmonary Edema - diagnosis ; Pulmonary Edema - etiology ; Risk Factors ; ROC Curve ; ST Elevation Myocardial Infarction - blood ; ST Elevation Myocardial Infarction - complications ; Transluminal angioplasty
Là 1 phần của: Brazilian journal of medical and biological research, 2019-01, Vol.52 (12), p.e9124-e9124
Mô tả: Carbohydrate antigen 125 (CA125) has long been used as an ovarian cancer biomarker. However, because it is not specific for ovarian cells, CA125 could also be used to monitor congestion and inflammation in heart disease. Acute heart failure (HF) is used to identify patients with a worse prognosis in ST-segment elevation myocardial infarction (STEMI). We aimed to determine the association of CA125 with acute HF in STEMI and to compare CA125 with N-terminal pro brain natriuretic peptide (NTproBNP) with a cross-sectional study. At admission, patients were examined to define Killip class and then underwent coronary angioplasty. Blood samples, preferably taken in the hemodynamic ward, were centrifuged (1500 g for 15 min at ambient temperature) and stored at -80°C until biomarker assays were performed. Patients were divided into two groups according to the presence or absence of congestion. Patients in Killip class ≥II were in the congestion group and those with Killip
Nơi xuất bản: Brazil: Associacao Brasileira de Divulgacao Cientifica (ABDC)
Ngôn ngữ: English;Portuguese
Số nhận dạng: ISSN: 0100-879X
ISSN: 1414-431X
EISSN: 1414-431X
DOI: 10.1590/1414-431X20199124
PMID: 31826182
Nguồn: SciELO
Geneva Foundation Free Medical Journals at publisher websites
MEDLINE
PubMed Central
Directory of Open Access Journals

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Carbohydrate antigen 125 predicts pulmonary congestion in patients with ST-segment elevation myocardial infarction

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