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Factors Associated with Mortality in Patients Hospitalized with COVID-19 Using Generalized Linear Model (Ordinal Logistic Regression) in North of Iran

Majallah-i dānishgāh-i ulū m-i pizishkī Māzandarān, 2022-11, Vol.32 (214), p.143-152 [Peer Reviewed Journal]

ISSN: 1735-9260 ;EISSN: 1735-9279

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  • Title:
    Factors Associated with Mortality in Patients Hospitalized with COVID-19 Using Generalized Linear Model (Ordinal Logistic Regression) in North of Iran
  • Author: Faezeh Sadat Movahedi ; Jamshid Yazdani Charati ; Seyed Nouraddin Mousavinasab ; Mohammad Sadegh Rezai ; Fatemeh Safari Haji Kolaei
  • Subjects: covid-19 ; generalized linear model ; mortality ; odds ratio ; ordinal logistic ; risk factor
  • Is Part Of: Majallah-i dānishgāh-i ulū m-i pizishkī Māzandarān, 2022-11, Vol.32 (214), p.143-152
  • Description: Background and purpose: Controlling the severity and death of the COVID-19 disease is still a major challenge. This research aimed at identifying the factors associated with mortality in hospitalized patients with COVID-19 applying generalized linear model. Materials and methods: In this cross-sectional study, demographic and clinical data of COVID-19 patients hospitalized with positive RT-PCR test results (n=6759) in Mazandaran hospitals (August 2019) were obtained from the national registration system for COVID-19. SPSS V27 and R V4.0 were used for data analyses and multivariate generalized linear model test with an ordinal logistic scale was applied. Results: Findings showed that full recovery and relative recovery occurred in 5888 (87.11%) and 400 (5.92%) patients, respectively. Mortality rate was 6.97%. The chance of death in patients with relative recovery (49.55%) compared with those with full recovery (21.61%) was almost 2.3 times higher. Predictors of mortality in these patients included age over 60 years (OR: 1.60), ICU admission (OR: 5.09), intubation (OR: 4.10), SpO2≤ 93% (OR: 2.41), cancer (OR: 1.74), diabetes (OR: 1.29), heart disease (OR: 1.41), and chronic kidney disease (OR: 2.17). Conclusion: Specific and timely medical care, considering the mentioned risk factors, should be introduced and provided to prevent mortality in patients hospitalized with COVID-19.
  • Publisher: Mazandaran University of Medical Sciences
  • Language: English
  • Identifier: ISSN: 1735-9260
    EISSN: 1735-9279
  • Source: Directory of Open Access Journals
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