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Uterine vascular resistance and other maternal factors associated with the risk of developing hypertension during pregnancy

Brazilian journal of medical and biological research, 2021-01, Vol.54 (1), p.e10118-e10118 [Peer Reviewed Journal]

COPYRIGHT 2021 Associacao Brasileira de Divulgacao Cientifica (ABDC) ;COPYRIGHT 2021 Associacao Brasileira de Divulgacao Cientifica (ABDC) ;Copyright Revista Brasileira de Pesquisas Medicas 2021 ;This work is licensed under a Creative Commons Attribution 4.0 International License. ;ISSN: 0100-879X ;ISSN: 1414-431X ;EISSN: 1414-431X ;DOI: 10.1590/1414-431X202010118 ;PMID: 33237124

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Title:
Uterine vascular resistance and other maternal factors associated with the risk of developing hypertension during pregnancy
Author: Martins, L A B ; Veiga, E C A ; Ribeiro, C C C ; Simões, V M F ; Cardoso, V C ; Bettiol, H ; Barbieri, M A ; Cavalli, R C
Subjects: Adolescent ; Adult ; Arteries ; BIOLOGY ; Body weight ; Child ; Childbirth ; Female ; Gestational Age ; Gestational hypertension ; Humans ; Hypertension ; Hypertension, Pregnancy-Induced - epidemiology ; Hypertension, Pregnancy-Induced - etiology ; Maternal Age ; MEDICINE, RESEARCH & EXPERIMENTAL ; Middle Aged ; Morbidity ; Obesity ; Parity ; Pre-eclampsia ; Pre-Eclampsia - epidemiology ; Pre-Eclampsia - etiology ; Pregnancy ; Pregnancy Outcome ; Pregnant women ; Prospective Studies ; Relative risk ; Risk Factors ; Uterus ; Uterus - physiopathology ; Vascular Resistance ; Young Adult
Is Part Of: Brazilian journal of medical and biological research, 2021-01, Vol.54 (1), p.e10118-e10118
Description: Gestational hypertension and pre-eclampsia are important causes of perinatal morbidity. The objective of the present study was to determine the increase in relative risk for developing hypertensive disorders of pregnancy based on the evaluation of pregnant women between 20 and 25 weeks of gestation, and to correlate the findings at this period with the outcome of pregnancy. We conducted a prospective cohort study, with a convenience sample of 1417 patients evaluated at this gestational age, of which 1306 were contacted at childbirth. We detected an increased relative risk of 2.69 (95%CI: 1.86 to 3.89) associated with pulsatility index of the uterine arteries, a 2.8 increase (95%CI: 1.58 to 5.03) in relative risk attributed to maternal age above 35 years, a 1.68 increase (95%CI: 1.17 to 2.40) attributed to parity greater than or equal to 3, and a 5.35 increase (95%CI: 4.18 to 6.85) attributed to chronic hypertension and obesity, with a progressive increase in relative risk according to the degree of overweight, i.e., grades 1, 2, 3, and morbid obesity (2.58, 3.06, 5.84, and 7.28, respectively).
Publisher: Brazil: Associacao Brasileira de Divulgacao Cientifica (ABDC)
Language: English;Portuguese
Identifier: ISSN: 0100-879X
ISSN: 1414-431X
EISSN: 1414-431X
DOI: 10.1590/1414-431X202010118
PMID: 33237124
Source: SciELO
GFMER Free Medical Journals
MEDLINE
PubMed Central
DOAJ Directory of Open Access Journals

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Uterine vascular resistance and other maternal factors associated with the risk of developing hypertension during pregnancy

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