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Short- and Long-Term Clinical Outcomes for Patients With Takotsubo Syndrome and Patients With Myocardial Infarction: A Report From the Swedish Coronary Angiography and Angioplasty Registry

Journal of the American Heart Association, 2021-09, Vol.10 (17), p.e017290-e017290 [Tạp chí có phản biện]

2021 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. ;ISSN: 2047-9980 ;EISSN: 2047-9980 ;DOI: 10.1161/JAHA.119.017290 ;PMID: 34465127

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Short- and Long-Term Clinical Outcomes for Patients With Takotsubo Syndrome and Patients With Myocardial Infarction: A Report From the Swedish Coronary Angiography and Angioplasty Registry
Tác giả: Redfors, Björn ; Jha, Sandeep ; Thorleifsson, Sigurdur ; Jernberg, Tomas ; Angerås, Oskar ; Frobert, Ole ; Petursson, Petur ; Tornvall, Per ; Sarno, Giovanna ; Ekenbäck, Christina ; Ravn-Fisher, Annika ; Y-Hassan, Shams ; Lyon, Alexander R ; James, Stefan ; Erlinge, David ; Omerovic, Elmir
Chủ đề: acute heart failure ; Aged ; Aged, 80 and over ; cardiogenic shock ; Coronary Angiography ; Female ; Heart Failure ; Humans ; Male ; Medicin och hälsovetenskap ; Middle Aged ; mortality rate ; Non-ST Elevated Myocardial Infarction - diagnostic imaging ; Non-ST Elevated Myocardial Infarction - mortality ; Non-ST Elevated Myocardial Infarction - therapy ; non-ST-segment-elevation myocardial infarction ; Original Research ; Registries ; Risk Factors ; Shock, Cardiogenic - therapy ; ST Elevation Myocardial Infarction - diagnostic imaging ; ST Elevation Myocardial Infarction - mortality ; ST Elevation Myocardial Infarction - therapy ; ST-segment-elevation myocardial infarction ; Sweden - epidemiology ; Swedish Coronary Angiography and Angioplasty Registry ; Takotsubo Cardiomyopathy - diagnostic imaging ; Takotsubo Cardiomyopathy - mortality ; Takotsubo Cardiomyopathy - therapy ; Takotsubo syndrome
Là 1 phần của: Journal of the American Heart Association, 2021-09, Vol.10 (17), p.e017290-e017290
Mô tả: Background Takotsubo syndrome (TS) is a potentially life-threatening acute cardiac syndrome with a clinical presentation similar to myocardial infarction and for which the natural history, management, and outcome remain incompletely understood. Our aim was to assess the relative short-term mortality risk of TS, ST-segment-elevation myocardial infarction (STEMI), and non-STEMI (NSTEMI) and to identify predictors of in-hospital complications and poor prognosis in patients with TS. Methods and Results This is an observational cohort study based on the data from the SCAAR (Swedish Coronary Angiography and Angioplasty Registry). We included all patients (n=117 720) who underwent coronary angiography in Sweden attributed to TS (N=2898 [2.5%]), STEMI (N=48 493 [41.2%]), or NSTEMI (N=66 329 [56.3%]) between January 2009 and February 2018. We compared patients with TS to those with NSTEMI or STEMI. The primary end point was all-cause mortality at 30 days. Secondary outcomes were acute heart failure (Killip Class ≥2) and cardiogenic shock (Killip Class 4) at the time of angiography. Patients with TS were more often women compared with patients with STEMI or NSTEMI. TS was associated with unadjusted and adjusted 30-day mortality risks lower than STEMI (adjusted hazard ratio [adjHR], 0.60; 95% CI, 0.48-0.76; <0.001), but higher than NSTEMI (adjHR, 2.70; 95% CI, 2.14-3.41; <0.001). Compared with STEMI, TS was associated with a similar risk of acute heart failure (adjHR, 1.26; 95% CI, 0.91-1.76; =0.16) but a lower risk of cardiogenic shock (adjHR, 0.55; 95% CI, 0.34-0.89; =0.02). The relative 30-day mortality risk for TS versus STEMI and NSTEMI was higher for smokers than nonsmokers (adjusted interaction STEMI=0.01 and interaction NSTEMI=0.01). Conclusions The 30-day mortality rate in TS was higher than in NSTEMI but lower than STEMI despite a similar risk of acute heart failure in TS and STEMI. Among patients with TS, smoking was an independent predictor of mortality.
Nơi xuất bản: England: John Wiley and Sons Inc
Ngôn ngữ: English
Số nhận dạng: ISSN: 2047-9980
EISSN: 2047-9980
DOI: 10.1161/JAHA.119.017290
PMID: 34465127
Nguồn: GFMER Free Medical Journals
MEDLINE
PubMed Central
SWEPUB Freely available online
Wiley Blackwell Open Access Titles
ROAD: Directory of Open Access Scholarly Resources
DOAJ Directory of Open Access Journals

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Short- and Long-Term Clinical Outcomes for Patients With Takotsubo Syndrome and Patients With Myocardial Infarction: A Report From the Swedish Coronary Angiography and Angioplasty Registry

2021 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. ;ISSN: 2047-9980 ;EISSN: 2047-9980 ;DOI: 10.1161/JAHA.119.017290 ;PMID: 34465127

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