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Regulation of Immune Function by Polyphenols

Journal of immunology research, 2018-01, Vol.2018, p.1264074-8 [Peer Reviewed Journal]

Copyright © 2018 Sujuan Ding et al. ;Copyright © 2018 Sujuan Ding et al.; This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ;Copyright © 2018 Sujuan Ding et al. 2018 ;ISSN: 2314-8861 ;EISSN: 2314-7156 ;DOI: 10.1155/2018/1264074 ;PMID: 29850614

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Title:
Regulation of Immune Function by Polyphenols
Author: Ding, Sujuan ; Jiang, Hongmei ; Fang, Jun
Wang, Kai ; Kai Wang
Subjects: Acids ; Allergic diseases ; Apoptosis ; Biochemistry ; Cancer ; Chemistry ; Curcumin ; Environmental changes ; Environmental regulations ; Environmental stress ; Epigallocatechin gallate ; Epigenetics ; Flavonoids ; Gangrene ; Gene expression ; Hypersensitivity ; Immune response ; Immune system ; Immunity ; Immunology ; Inflammation ; Intestine ; Metabolites ; Mucosal immunity ; Nutrition ; Nutrition research ; Polyphenols ; Proteins ; Regulators ; Review ; Rodents ; Signal transduction ; TNF inhibitors ; Tumor necrosis factor-TNF
Is Part Of: Journal of immunology research, 2018-01, Vol.2018, p.1264074-8
Description: Immune dysfunction is caused by various factors, including changes in relevant immune regulators and environmental stress. Immune system imbalance leads to a variety of diseases in humans. Nutrition may play an essential role in immunity by interfering with proinflammatory cytokine synthesis, immune cell regulation, and gene expression. Polyphenols, one of many categories of natural substances, exhibit a range of biological activities. Polyphenols promote immunity to foreign pathogens via various pathways. Different immune cells express multiple types of polyphenol receptors that recognise and allow cellular uptake of polyphenols, which subsequently activate signalling pathways to initiate immune responses. Furthermore, the polyphenols curcumin and epigallocatechin gallate can induce epigenetic changes in cells. In summary, polyphenols can be used to regulate intestinal mucosal immune responses, allergic diseases, and antitumour immunity.
Publisher: Egypt: Hindawi
Language: English
Identifier: ISSN: 2314-8861
EISSN: 2314-7156
DOI: 10.1155/2018/1264074
PMID: 29850614
Source: PubMed Central
ProQuest Central
DOAJ Directory of Open Access Journals

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Regulation of Immune Function by Polyphenols

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