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The impact of frailty on prolonged hospitalization and mortality in elderly inpatients in Vietnam: a comparison between the frailty phenotype and the Reported Edmonton Frail Scale

Clinical interventions in aging, 2019-01, Vol.14, p.381-388 [Peer Reviewed Journal]

COPYRIGHT 2019 Dove Medical Press Limited ;2019. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 Nguyen et al. This work is published and licensed by Dove Medical Press Limited 2019 ;ISSN: 1178-1998 ;ISSN: 1176-9092 ;EISSN: 1178-1998 ;DOI: 10.2147/CIA.S189122 ;PMID: 30863032

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Title:
The impact of frailty on prolonged hospitalization and mortality in elderly inpatients in Vietnam: a comparison between the frailty phenotype and the Reported Edmonton Frail Scale
Author: Nguyen, Anh Trung ; Nguyen, Thanh Xuan ; Nguyen, Tu N ; Nguyen, Thu Hoai Thi ; Pham, Thang ; Cumming, Robert ; Hilmer, Sarah N ; Vu, Huyen Thi Thanh
Subjects: Aged ; Aged patients ; Aged, 80 and over ; Developing countries ; elderly ; Female ; Frail elderly ; Frail Elderly - statistics & numerical data ; Frailty ; Geriatric Assessment ; Hospital Mortality - trends ; Hospital utilization ; Humans ; Inpatients ; LDCs ; Length of Stay ; Male ; Mortality ; Muscle weakness ; Older people ; Original Research ; Patient outcomes ; Phenotype ; Prevalence ; Proportional Hazards Models ; Statistics ; Survival Analysis ; Vietnam ; Vietnam - epidemiology
Is Part Of: Clinical interventions in aging, 2019-01, Vol.14, p.381-388
Description: To investigate the impact of frailty on outcomes in older hospitalized patients, including prolonged length of stay and all-cause mortality 6 months after admission, using both the frailty phenotype and the Reported Edmonton Frail Scale (REFS). This study is the follow-up phase of a study designed to investigate the prevalence of frailty and its impact on adverse outcomes in older hospitalized patients at the National Geriatric Hospital in Hanoi, Vietnam. A total of 461 participants were included, with a mean age 76.2±8.9 years, and 56.8% were female. The prevalence of frailty was 31.9% according to the REFS and 35.4% according to Fried's criteria. The kappa coefficient was 0.57 (95% CI =0.49-0.66) between the two frailty criteria in identifying frail and non-frail participants. There was a trend toward increasing the likelihood of prolonged hospitalization in participants with frailty defined by Fried's criteria (adjusted OR =1.49, 95% CI =0.94-2.35) or by REFS (adjusted OR =1.43, 95% CI =0.89-2.29). During 6 months of follow-up, 210 were lost and 18/251 (7.2%) participants died. Mortality was higher in those with frailty defined by either Fried's criteria or REFS. On multivariable survival analysis, adjusted HRs for mortality were 2.65 (95% CI =1.02-6.89) for Fried's criteria and 4.19 (95% CI =1.59-10.99) for REFS. Fried's frailty phenotype or REFS can be used as a screening tool to detect frailty in older inpatients in Vietnam and predict mortality. Frailty screening can help prioritize targeted frailty-tailored treatments, such as nutrition, early mobility and medication review, for these vulnerable patients to improve clinical outcomes.
Publisher: New Zealand: Dove Medical Press Limited
Language: English
Identifier: ISSN: 1178-1998
ISSN: 1176-9092
EISSN: 1178-1998
DOI: 10.2147/CIA.S189122
PMID: 30863032
Source: DOAJ Directory of Open Access Journals
GFMER Free Medical Journals
MEDLINE
PubMed Central
ProQuest Central
Dove Press Free

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The impact of frailty on prolonged hospitalization and mortality in elderly inpatients in Vietnam: a comparison between the frailty phenotype and the Reported Edmonton Frail Scale

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