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Fetal death after the introduction of COVID-19 mitigation measures in Sweden, Denmark and Norway: a registry-based study

Scientific reports, 2022-11, Vol.12 (1), p.20625-20625 [Peer Reviewed Journal]

2022. The Author(s). ;The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2022 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-022-25036-1 ;PMID: 36450919

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Title:
Fetal death after the introduction of COVID-19 mitigation measures in Sweden, Denmark and Norway: a registry-based study
Author: Magnus, Maria C ; Oakley, Laura L ; Hansen, Anne V ; Örtqvist, Anne K ; Petersen, Tanja G ; Mortensen, Laust H ; Bliddal, Mette ; Andersen, Anne-Marie Nybo ; Stephansson, Olof ; Håberg, Siri E
Subjects: Abortion, Spontaneous - epidemiology ; Communicable Disease Control ; Coronaviruses ; COVID-19 ; COVID-19 - epidemiology ; COVID-19 - prevention & control ; Death ; Denmark - epidemiology ; Female ; Fetuses ; Humans ; Medicin och hälsovetenskap ; Miscarriage ; Norway - epidemiology ; Pandemics ; Pandemics - prevention & control ; Pregnancy ; Registries ; Stillbirth ; Stillbirth - epidemiology ; Sweden - epidemiology
Is Part Of: Scientific reports, 2022-11, Vol.12 (1), p.20625-20625
Description: It remains unclear whether the rate of fetal death has changed during the COVID-19 pandemic. We assessed the impact of COVID-19 mitigation measures on fetal death in Sweden (449,347 births), Denmark (290,857 pregnancies) and Norway (261,057 pregnancies) using robust population-based registry data. We used Cox regression to assess the impact of the implementation of pandemic mitigation measures on March 12th, 2020, on miscarriage (fetal loss before gestational week 22) and stillbirth (fetal loss after gestational week 22). A total of 11% of 551,914 pregnancies in Denmark and Norway ended in miscarriage, while the proportion of stillbirths among 937,174 births across the three countries was 0.3%. There was no difference in the risk of fetal death during the year following pandemic mitigation measures. For miscarriage, the combined hazard ratio (HR) for Norway and Denmark was 1.01 (95% CI 0.98, 1.03), and for stillbirth, the combined HR for all three countries was 0.99 (95% CI 0.89, 1.09). We observed a slightly decreased risk of miscarriage during the first 4 months, with an HR of 0.94 (95% CI 0.90, 0.99) after lockdown. In conclusion, the risk of fetal death did not change after the implementation of COVID-19 pandemic mitigation measures in the three Scandinavian countries.
Publisher: England: Nature Publishing Group
Language: English
Identifier: ISSN: 2045-2322
EISSN: 2045-2322
DOI: 10.1038/s41598-022-25036-1
PMID: 36450919
Source: MEDLINE
PubMed Central
SWEPUB Freely available online
Coronavirus Research Database
ProQuest Central
DOAJ Directory of Open Access Journals

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Fetal death after the introduction of COVID-19 mitigation measures in Sweden, Denmark and Norway: a registry-based study

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