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Treatment of stimulant use disorder: A systematic review of reviews

PloS one, 2020-06, Vol.15 (6), p.e0234809 [Peer Reviewed Journal]

COPYRIGHT 2020 Public Library of Science ;COPYRIGHT 2020 Public Library of Science ;2020 Ronsley et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2020 Ronsley et al 2020 Ronsley et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0234809 ;PMID: 32555667

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Title:
Treatment of stimulant use disorder: A systematic review of reviews
Author: Ronsley, Claire ; Nolan, Seonaid ; Knight, Rod ; Hayashi, Kanna ; Klimas, Jano ; Walley, Alex ; Wood, Evan ; Fairbairn, Nadia
Hashimoto, Kenji
Subjects: Acetylcysteine ; Acupuncture ; Agonists ; Amphetamines ; Anticonvulsants ; Anticonvulsants - therapeutic use ; Antidepressants ; Antidepressive Agents - therapeutic use ; Antipsychotic Agents - therapeutic use ; Antipsychotics ; Central nervous system stimulants ; Central Nervous System Stimulants - therapeutic use ; Clinical trials ; Cocaine ; Cognitive ability ; Cognitive Behavioral Therapy ; Complications and side effects ; Contingency ; Disulfiram ; Dopamine ; Dopamine Agonists - therapeutic use ; Drug addiction ; Drug therapy ; Drug use ; Evaluation ; Health services ; Hospitals ; Humans ; Identification methods ; Intervention ; Literature reviews ; Management ; Medical protocols ; Medical treatment ; Medicine ; Medicine and Health Sciences ; Meta-analysis ; Methamphetamine ; Methods ; Opioids ; Pharmacology ; Physical Sciences ; Research and Analysis Methods ; Reviews ; Stimulants ; Studies ; Substance-Related Disorders - drug therapy ; Substance-Related Disorders - pathology ; Substance-Related Disorders - therapy ; Synthesis ; Systematic review
Is Part Of: PloS one, 2020-06, Vol.15 (6), p.e0234809
Description: Stimulant use disorder contributes to a substantial worldwide burden of disease, although evidence-based treatment options are limited. This systematic review of reviews aims to: (i) synthesize the available evidence on both psychosocial and pharmacological interventions for the treatment of stimulant use disorder; (ii) identify the most effective therapies to guide clinical practice, and (iii) highlight gaps for future study. A systematic database search was conducted to identify systematic reviews and meta-analyses. Eligible studies were those that followed standard systematic review methodology and assessed randomized controlled trials focused on the efficacy of interventions for stimulant use disorder. Articles were critically appraised using an assessment tool adapted from Palmeteer et al. and categorized for quality as 'core' or 'supplementary' reviews. Evidence from the included reviews were further synthesized according to pharmacological or non-pharmacological management themes. Of 476 identified records, 29 systematic reviews examining eleven intervention modalities were included. The interventions identified include: contingency management, cognitive behavioural therapy, acupuncture, antidepressants, dopamine agonists, antipsychotics, anticonvulsants, disulfiram, opioid agonists, N-Acetylcysteine, and psychostimulants. There was sufficient evidence to support the efficacy of contingency management programs for treatment of stimulant use disorder. Psychostimulants, n-acetylcysteine, opioid agonist therapy, disulfiram and antidepressant pharmacological interventions were found to have insufficient evidence to support or discount their use. Results of this review do not support the use of all other treatment options. The results of this review supports the use of contingency management interventions for the treatment of stimulant use disorder. Although evidence to date is insufficient to support the clinical use of psychostimulants, our results demonstrate potential for future research in this area. Given the urgent need for effective pharmacological treatments for stimulant use disorder, high-quality primary research focused on the role of psychostimulant medications for the treatment of stimulant use disorder is needed.
Publisher: United States: Public Library of Science
Language: English
Identifier: ISSN: 1932-6203
EISSN: 1932-6203
DOI: 10.1371/journal.pone.0234809
PMID: 32555667
Source: Public Library of Science (PLoS) Journals Open Access
GFMER Free Medical Journals
MEDLINE
PubMed Central
ProQuest Central
DOAJ Directory of Open Access Journals

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Treatment of stimulant use disorder: A systematic review of reviews

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