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Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients

The New England journal of medicine, 2023-04, Vol.388 (15), p.1353-1364 [Peer Reviewed Journal]

Copyright © 2023 Massachusetts Medical Society. All rights reserved. ;Copyright © 2023 Massachusetts Medical Society. ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa2215024 ;PMID: 36876740

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Title:
Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients
Author: Nissen, Steven E. ; Lincoff, A. Michael ; Brennan, Danielle ; Ray, Kausik K. ; Mason, Denise ; Kastelein, John J.P. ; Thompson, Paul D. ; Libby, Peter ; Cho, Leslie ; Plutzky, Jorge ; Bays, Harold E. ; Moriarty, Patrick M. ; Menon, Venu ; Grobbee, Diederick E. ; Louie, Michael J. ; Chen, Chien-Feng ; Li, Na ; Bloedon, LeAnne ; Robinson, Paula ; Horner, Maggie ; Sasiela, William J. ; McCluskey, Jackie ; Davey, Deborah ; Fajardo-Campos, Pedro ; Petrovic, Predrag ; Fedacko, Jan ; Zmuda, Witold ; Lukyanov, Yury ; Nicholls, Stephen J.
Subjects: Administration, Oral ; Cardiology ; Cardiovascular Diseases - drug therapy ; Cardiovascular Diseases - epidemiology ; Cardiovascular Diseases - prevention & control ; Cardiovascular Diseases - surgery ; Clinical Medicine ; Clinical Medicine General ; Coronary Disease ; Double-Blind Method ; Fatty Acids - administration & dosage ; Fatty Acids - adverse effects ; Fatty Acids - therapeutic use ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects ; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use ; Hypolipidemic Agents - administration & dosage ; Hypolipidemic Agents - adverse effects ; Hypolipidemic Agents - therapeutic use ; Lipids ; Myocardial Infarction ; Myocardial Infarction - epidemiology ; Myocardial Infarction - prevention & control ; Myocardial Revascularization ; Outpatient-Based Clinical Medicine ; Prevention ; Stroke - epidemiology ; Stroke - prevention & control
Is Part Of: The New England journal of medicine, 2023-04, Vol.388 (15), p.1353-1364
Description: In this randomized trial, statin-intolerant patients with, or at high risk for, CVD received bempedoic acid or placebo. Bempedoic acid reduced LDL cholesterol and the risk of cardiovascular events.
Publisher: United States: Massachusetts Medical Society
Language: English
Identifier: ISSN: 0028-4793
EISSN: 1533-4406
DOI: 10.1056/NEJMoa2215024
PMID: 36876740
Source: ProQuest One Psychology
AUTh Library subscriptions: ProQuest Central
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Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients

Copyright © 2023 Massachusetts Medical Society. All rights reserved. ;Copyright © 2023 Massachusetts Medical Society. ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa2215024 ;PMID: 36876740

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