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A brief-review of the risk factors for covid-19 severity

Revista de saúde pública, 2020-01, Vol.54, p.60-60 [Peer Reviewed Journal]

This work is licensed under a Creative Commons Attribution 4.0 International License. ;ISSN: 0034-8910 ;ISSN: 1518-8787 ;EISSN: 1518-8787 ;DOI: 10.11606/s1518-8787.2020054002481 ;PMID: 32491116

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  • Title:
    A brief-review of the risk factors for covid-19 severity
  • Author: Rod, J E ; Oviedo-Trespalacios, Oscar ; Cortes-Ramirez, Javier
  • Subjects: Betacoronavirus ; Brief Communication ; Coronavirus Infections - epidemiology ; COVID-19 ; Diabetes Complications ; fatal outcome ; Female ; Health Policy & Services ; Humans ; Male ; Pandemics ; Pneumonia, Viral - epidemiology ; review ; Risk Assessment ; Risk Factors ; SARS-CoV-2 ; Severity of Illness Index
  • Is Part Of: Revista de saúde pública, 2020-01, Vol.54, p.60-60
  • Description: The World Health Organization has emphasized that one of the most important questions to address regarding the covid-19 pandemic is to understand risk factors for disease severity. We conducted a brief review that synthesizes the available evidence and provides a judgment on the consistency of the association between risk factors and a composite end-point of severe-fatal covid-19. Additionally, we also conducted a comparability analysis of risk factors across 17 studies. We found evidence supporting a total of 60 predictors for disease severity, of which seven were deemed of high consistency, 40 of medium and 13 of low. Among the factors with high consistency of association, we found age, C-reactive protein, D-dimer, albumin, body temperature, SOFA score and diabetes. The results suggest that diabetes might be the most consistent comorbidity predicting disease severity and that future research should carefully consider the comparability of reporting cases, factors, and outcomes along the different stages of the natural history of covid-19.
  • Publisher: Brazil: Faculdade de Saúde Pública da Universidade de São Paulo
  • Language: English;Portuguese
  • Identifier: ISSN: 0034-8910
    ISSN: 1518-8787
    EISSN: 1518-8787
    DOI: 10.11606/s1518-8787.2020054002481
    PMID: 32491116
  • Source: SciELO
    Geneva Foundation Free Medical Journals at publisher websites
    MEDLINE
    PubMed Central
    Directory of Open Access Journals

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