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The Role of Different Inflammatory Indices in the Diagnosis of COVID-19

International journal of general medicine, 2021-01, Vol.14, p.7843-7853 [Peer Reviewed Journal]

2021 Eissa et al. ;COPYRIGHT 2021 Dove Medical Press Limited ;2021. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 Eissa et al. 2021 Eissa et al. ;ISSN: 1178-7074 ;EISSN: 1178-7074 ;DOI: 10.2147/IJGM.S337488 ;PMID: 34795505

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  • Title:
    The Role of Different Inflammatory Indices in the Diagnosis of COVID-19
  • Author: Eissa, Marwa ; Shaarawy, Sabry ; Abdellateif, Mona S
  • Subjects: Bacterial infections ; C-reactive protein ; Comparative analysis ; COVID-19 ; Health aspects ; Inflammation ; inflammatory index ; Lymphocytes ; Medical research ; Medicine, Experimental ; Mortality ; Original Research ; platelets ; sii
  • Is Part Of: International journal of general medicine, 2021-01, Vol.14, p.7843-7853
  • Description: To assess the role of different inflammatory indices in the diagnosis of COVID-19 infection. The neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), platelet-to-lymphocyte ratio (PLR), derived NLR (dNLR), neutrophil to lymphocyte, platelet ratio (NLPR), systemic inflammation index (SII), aggregate index of systemic inflammation (AISI), systemic inflammation response index (SIRI) and C-reactive protein-to-lymphocyte ratio (CRP/L) were assessed in 88 COVID-19 patients compared to 41 healthy control subjects. The NLR, PLR, NLPR, SIRI, and CRP/L were significantly increased, while LMR was significantly decreased in COVID-19 patients compared to the control group (P = 0.008, 0.011, <0.001, 0.032, 0.002 and P < 0.001; respectively). The AUC for the assessed indices was LMR (0.738, P = 0.008), NLPR (0.721, P < 0.001), CRP/L (0.692, P = 0.002), NLR (0.649, P < 0.001), PLR (0.643, P = 0.011), SIRI (0.623, P = 0.032), dNLR (0.590, P = 0.111), SII (0.571, P = 0.207), and AISI (0.567, P-0.244). Multivariate analysis showed that NLPR >0.011 (OR: 38.751, P = 0.014), and CRP/L >7.6 (OR: 7.604, P = 0.022) are possible independent diagnostic factors for COVID-19 infection. NLPR and CRP/L could be potential independent diagnostic factors for COVID-19 infection.
  • Publisher: New Zealand: Dove Medical Press Limited
  • Language: English
  • Identifier: ISSN: 1178-7074
    EISSN: 1178-7074
    DOI: 10.2147/IJGM.S337488
    PMID: 34795505
  • Source: GFMER Free Medical Journals
    PubMed Central
    DOVE Medical Press Journals
    Coronavirus Research Database
    ROAD: Directory of Open Access Scholarly Resources
    ProQuest Central
    DOAJ Directory of Open Access Journals
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