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Important Flavonoids and Their Role as a Therapeutic Agent

Molecules (Basel, Switzerland), 2020-11, Vol.25 (22), p.5243 [Peer Reviewed Journal]

2020. This work is licensed under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2020 by the authors. 2020 ;ISSN: 1420-3049 ;EISSN: 1420-3049 ;DOI: 10.3390/molecules25225243 ;PMID: 33187049

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Title:
Important Flavonoids and Their Role as a Therapeutic Agent
Author: Ullah, Asad ; Munir, Sidra ; Badshah, Syed Lal ; Khan, Noreen ; Ghani, Lubna ; Poulson, Benjamin Gabriel ; Emwas, Abdul-Hamid ; Jaremko, Mariusz
Subjects: Alzheimer Disease - drug therapy ; Alzheimer Disease - prevention & control ; Angiogenesis ; Animal models ; Animals ; Anti-Inflammatory Agents - chemistry ; Anti-Inflammatory Agents - pharmacology ; Antifungal Agents - chemistry ; Antifungal Agents - pharmacology ; Antimalarials - chemistry ; Antimalarials - pharmacology ; Antineoplastic Agents - chemistry ; Antineoplastic Agents - pharmacology ; Antioxidants ; Antioxidants - chemistry ; Antioxidants - pharmacology ; antioxidative ; Antiviral activity ; Antiviral Agents - chemistry ; Antiviral Agents - pharmacology ; Bioavailability ; Biological effects ; Breast cancer ; Cancer therapies ; Cardiovascular System - drug effects ; Cell cycle ; Cell growth ; Chemical compounds ; Colorectal cancer ; Cytotoxicity ; Drug dosages ; Flavonoids ; Flavonoids - chemistry ; Flavonoids - economics ; Flavonoids - pharmacology ; Fruits ; Humans ; Hypoglycemic Agents - chemistry ; Hypoglycemic Agents - pharmacology ; Inflammation ; Kinases ; Liver cancer ; Medicinal plants ; Metabolism ; Metabolites ; Mice ; Mode of action ; Nanoparticles ; Nervous System - drug effects ; Neurons - drug effects ; Neuroprotection ; neuroprotective ; Neuroprotective Agents - chemistry ; Neuroprotective Agents - pharmacology ; Pharmacology ; Phytochemicals ; Plant Extracts - pharmacology ; Plant Leaves - chemistry ; Plants (botany) ; Plants - chemistry ; Polyphenols ; Polyphenols - chemistry ; Polyphenols - pharmacology ; quercetin ; Quercetin - chemistry ; Quercetin - pharmacology ; Rats ; Rats, Sprague-Dawley ; Rats, Wistar ; Review ; Stroke - drug therapy ; Stroke - prevention & control ; Vascular endothelial growth factor
Is Part Of: Molecules (Basel, Switzerland), 2020-11, Vol.25 (22), p.5243
Description: Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of medicinal benefits, including anticancer, antioxidant, anti-inflammatory, and antiviral properties. They also have neuroprotective and cardio-protective effects. These biological activities depend upon the type of flavonoid, its (possible) mode of action, and its bioavailability. These cost-effective medicinal components have significant biological activities, and their effectiveness has been proved for a variety of diseases. The most recent work is focused on their isolation, synthesis of their analogs, and their effects on human health using a variety of techniques and animal models. Thousands of flavonoids have been successfully isolated, and this number increases steadily. We have therefore made an effort to summarize the isolated flavonoids with useful activities in order to gain a better understanding of their effects on human health.
Publisher: Switzerland: MDPI AG
Language: English
Identifier: ISSN: 1420-3049
EISSN: 1420-3049
DOI: 10.3390/molecules25225243
PMID: 33187049
Source: Open Access: DOAJ Directory of Open Access Journals
Open Access: PubMed Central
Geneva Foundation Free Medical Journals at publisher websites
AUTh Library subscriptions: ProQuest Central
MEDLINE
Alma/SFX Local Collection
Coronavirus Research Database

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Important Flavonoids and Their Role as a Therapeutic Agent

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