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Measurement of Health-Related Quality of Life Among Colorectal Cancer Patients Using the Vietnamese Value Set of the EQ-5D-5L

Patient preference and adherence, 2020-01, Vol.14, p.2427-2437 [Peer Reviewed Journal]

2020 Tran et al. ;2020. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2020 Tran et al. 2020 Tran et al. ;ISSN: 1177-889X ;EISSN: 1177-889X ;DOI: 10.2147/ppa.s281500 ;PMID: 33304097

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  • Title:
    Measurement of Health-Related Quality of Life Among Colorectal Cancer Patients Using the Vietnamese Value Set of the EQ-5D-5L
  • Author: Tran, Binh Thang ; Pham, Nhu Hiep ; Nguyen, Thanh Xuan ; Choi, Kui Son ; Sohn, Dae Kyung ; Kim, Sun-Young ; Suh, Jae Kyung ; Nguyen, Thuy Duyen ; Phan, Van Sang ; Tran, Dinh Trung ; Nguyen, The Thanh ; Nguyen, Thi Thanh Binh ; Nguyen, Minh Tu ; Oh, Jin-Kyoung
  • Subjects: Cancer therapies ; Chemotherapy ; Colorectal cancer ; eq-5d-5l ; Health economics ; Hospitals ; hrqol ; Medical diagnosis ; Medical records ; Medical research ; Mortality ; Normal distribution ; Original Research ; Patients ; Population ; Quality of life ; Questionnaires ; Radiation therapy ; Sociodemographics ; utility ; vietnam
  • Is Part Of: Patient preference and adherence, 2020-01, Vol.14, p.2427-2437
  • Description: Health-related quality of life (HRQoL) is an important construct in clinical settings, and it is crucial that it should be properly measured. As the EuroQol-5-dimensions-5 levels (EQ-5D-5L) is more effective for such measurement than the 3-level model, data on economic models, clinical studies, and public health evaluations previously collected through the EQ-5D-3L need to be revaluated using the EQ-5D-5L. This study evaluated colorectal cancer (CRC) patients' HRQoL scores using the Vietnamese EQ-5D-5L value set. The cross-sectional study included CRC patients treated at a tertiary public hospital. HRQoL was assessed using the EQ-5D-5L, and HRQoL utility scores were calculated using the Vietnamese value set. Tobit regression examined factors associated with HRQoL. The analysis included 197 CRC patients. Ages ranged from 20 to 87 years (M = 57.64, SD = 13.5); 42.2% and 57.8% were diagnosed with cancer of the colon or rectum/anus, respectively. Mean EQ-5D-5L was 0.561 (range, -0.5115 to 1). Most participants experienced anxiety/depression (88%), followed by pain/discomfort (87%), mobility (71%), usual activity (69%), and self-care (67%). Advanced CRC stage (stage II: β -0.303, se 0.08; stage III: β -0.305, se 0.07; stage IV: β -0.456, se 0.07) and surgery (β -0.113, se 0.05) were negatively associated with EQ-5D-5L scores. Advanced education (high school: β 0.273, se 0.07); college/vocational: β 0.134se 0.05; university/higher: Coef 0.213, se 0.08;) and older age (age group 35-44: β 0.253, se 0.10; 45-54: β 0.327, se 0.09; 55-64: β 0.355 se 0.09; 65+ β 0.204, se 0.09) were positively associated with EQ-5D-5L scores. Patients in advanced CRC stages or undergoing surgery experienced lower HRQoL and higher prevalence of anxiety/depression and pain/discomfort. Older age and high educational attainment predicted high HRQoL. This study provides information on CRC patients' health utility based on various patient characteristics, which can be used in future economic evaluations.
  • Publisher: New Zealand: Taylor & Francis Ltd
  • Language: English
  • Identifier: ISSN: 1177-889X
    EISSN: 1177-889X
    DOI: 10.2147/ppa.s281500
    PMID: 33304097
  • Source: Geneva Foundation Free Medical Journals at publisher websites
    PubMed Central
    DOVE Medical Press Journals
    ROAD: Directory of Open Access Scholarly Resources
    ProQuest Central
    DOAJ Directory of Open Access Journals
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