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2018 update of the EULAR recommendations for the management of Behçet’s syndrome

Annals of the rheumatic diseases, 2018-06, Vol.77 (6), p.808-818 [Peer Reviewed Journal]

Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. ;Copyright: 2018 © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. ;ISSN: 0003-4967 ;EISSN: 1468-2060 ;DOI: 10.1136/annrheumdis-2018-213225 ;PMID: 29625968

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Title:
2018 update of the EULAR recommendations for the management of Behçet’s syndrome
Author: Hatemi, Gulen ; Christensen, Robin ; Bang, Dongsik ; Bodaghi, Bahram ; Celik, Aykut Ferhat ; Fortune, Farida ; Gaudric, Julien ; Gul, Ahmet ; Kötter, Ina ; Leccese, Pietro ; Mahr, Alfred ; Moots, Robert ; Ozguler, Yesim ; Richter, Jutta ; Saadoun, David ; Salvarani, Carlo ; Scuderi, Francesco ; Sfikakis, Petros P ; Siva, Aksel ; Stanford, Miles ; Tugal-Tutkun, Ilknur ; West, Richard ; Yurdakul, Sebahattin ; Olivieri, Ignazio ; Yazici, Hasan
Subjects: Arthritis ; Behcet Syndrome - drug therapy ; Evidence-Based Medicine - methods ; Experts ; Gastroenterology ; Gastrointestinal Diseases - drug therapy ; Glucocorticoids - therapeutic use ; Humans ; Immunosuppressive Agents - therapeutic use ; Literature reviews ; Management ; Medical personnel ; Nervous system ; Nervous System Diseases - drug therapy ; Patients ; Physicians ; Surgery ; Systematic review ; Task forces ; Uveitis, Anterior - drug therapy ; Venous Thrombosis - drug therapy
Is Part Of: Annals of the rheumatic diseases, 2018-06, Vol.77 (6), p.808-818
Description: Several new treatment modalities with different mechanisms of action have been studied in patients with Behçet’s syndrome (BS). The aim of the current effort was to update the recommendations in the light of these new data under the auspices of the European League Against Rheumatism (EULAR) Standing Committee for Clinical Affairs. A task force was formed that included BS experts from different specialties including internal medicine, rheumatology, ophthalmology, dermatology, neurology, gastroenterology, oral health medicine and vascular surgery, along with a methodologist, a health professional, two patients and two fellows in charge of the systematic literature search. Research questions were determined using a Delphi approach. EULAR standardised operating procedures was used as the framework. Results of the systematic literature review were presented to the task force during a meeting. The former recommendations were modified or new recommendations were formed after thorough discussions followed by voting. The recommendations on the medical management of mucocutaneous, joint, eye, vascular, neurological and gastrointestinal involvement of BS were modified; five overarching principles and a new recommendation about the surgical management of vascular involvement were added. These updated, evidence-based recommendations are intended to help physicians caring for patients with BS. They also attempt to highlight the shortcomings of the available clinical research with the aim of proposing an agenda for further research priorities.
Publisher: England: BMJ Publishing Group LTD
Language: English
Identifier: ISSN: 0003-4967
EISSN: 1468-2060
DOI: 10.1136/annrheumdis-2018-213225
PMID: 29625968
Source: MEDLINE
ProQuest Central

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2018 update of the EULAR recommendations for the management of Behçet’s syndrome

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