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Case Report: Transcatheter aortic valve implantation using balloon-expandable bioprosthesis in patients with severe pure aortic regurgitation on noncalcified native valves: a series of cases

Frontiers in cardiovascular medicine, 2024-04, Vol.11, p.1365181 [Peer Reviewed Journal]

2024 Santos, Luz, Bastos, Barcelos, Abreu, Beck, Darnasser, Cruz, Matos and Carvalho. ;ISSN: 2297-055X ;EISSN: 2297-055X ;DOI: 10.3389/fcvm.2024.1365181 ;PMID: 38737717

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  • Title:
    Case Report: Transcatheter aortic valve implantation using balloon-expandable bioprosthesis in patients with severe pure aortic regurgitation on noncalcified native valves: a series of cases
  • Author: Santos, Luciano de Moura ; Luz, Larissa Santos ; Bastos, Vinicius Lelis ; Barcelos, Tulio Assunção ; Abreu, Frederico André Alves ; Beck, Leonardo Cogo ; Darnasser, Mohammed Jamal Aldin Hilal ; Cruz, Francisco de Assis ; Matos, Luis Carlos Vieira ; Carvalho, Jr, Wenderval Borges
  • Subjects: aortic regurgitation ; balloon-expandable valve bioprosthesis ; leak paravalvular ; pure native aortic valve regurgitation ; transcatheter aortic valve implantation
  • Is Part Of: Frontiers in cardiovascular medicine, 2024-04, Vol.11, p.1365181
  • Description: For individuals with pure aortic regurgitation (AR), transcatheter aortic valve implantation (TAVI) is cautiously recommended only for those with a high or prohibitive surgical risk. We aimed to describe the results of a case series of transcatheter implantation of a balloon-expandable aortic valve bioprosthesis (BEV) for the treatment of noncalcified native valve AR. From February 2022-November 2022, we performed TAVI in patients with severe pure AR. Cases were indicated on the basis of symptoms, high/prohibitive surgical risk, or patient refusal of conventional treatment. Five patients underwent successful TAVI. The mean age was 81.9 ± 6.6 years, 3 (60%) female and 5 (100%) in NYHA class III or IV. The baseline echocardiogram showed an ejection fraction of 49.0 ± 10.6% and left ventricular end-systolic diameter 28.5 ± 4.7 mm/m². The average area of the aortic annulus was 529.1 ± 47.0mm² and the area oversizing index was 17.6 ± 1.2%. In the 30-day follow-up, there were no cases of prosthesis embolization, annulus rupture, stroke, acute myocardial infarction, acute renal failure, hemorrhagic complication or death. One patient required a permanent pacemaker and another had a minor vascular complication. The clinical follow-up were 19.8 months (16.7-21.8). During this period, all patients remained alive and in NYHA class I or II. One of the patients developed a moderate paravalvular leak. TAVI with a BEV proved to be safe and effective in this small case series of patients with noncalcified native valve AR in a follow-up longer than 1 year.
  • Publisher: Switzerland: Frontiers Media S.A
  • Language: English
  • Identifier: ISSN: 2297-055X
    EISSN: 2297-055X
    DOI: 10.3389/fcvm.2024.1365181
    PMID: 38737717
  • Source: PubMed Central
    ROAD: Directory of Open Access Scholarly Resources
    DOAJ Directory of Open Access Journals
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