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Effect of accelerated rehabilitation on function after ankle sprain: randomised controlled trial

BMJ, 2010-05, Vol.340 (7756), p.1122-1122 [Peer Reviewed Journal]

Bleakley et al 2010 ;2010 BMJ Publishing Group Ltd ;Copyright BMJ Publishing Group LTD May 10, 2010 ;ISSN: 0959-8138 ;EISSN: 1468-5833 ;EISSN: 1756-1833 ;DOI: 10.1136/bmj.c1964 ;PMID: 20457737

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  • Title:
    Effect of accelerated rehabilitation on function after ankle sprain: randomised controlled trial
  • Author: Bleakley, Chris M ; O’Connor, Seán R ; Tully, Mark A ; Rocke, Laurence G ; MacAuley, Domhnall C ; Bradbury, Ian ; Keegan, Stephen ; McDonough, Suzanne M
  • Subjects: Adolescent ; Adult ; Aged ; Ankle ; Ankle Injuries - physiopathology ; Ankle Injuries - rehabilitation ; Departments ; Edema - etiology ; Exercise ; Exercise Therapy ; Experimentation ; Humans ; Middle Aged ; Pain - etiology ; Physical fitness ; Recovery of Function ; Rehabilitation ; Sports injuries ; Sprains and Strains - physiopathology ; Sprains and Strains - rehabilitation ; Studies ; Young Adult
  • Is Part Of: BMJ, 2010-05, Vol.340 (7756), p.1122-1122
  • Description: Objective To compare an accelerated intervention incorporating early therapeutic exercise after acute ankle sprains with a standard protection, rest, ice, compression, and elevation intervention. Design Randomised controlled trial with blinded outcome assessor. Setting Accident and emergency department and university based sports injury clinic. Participants 101 patients with an acute grade 1 or 2 ankle sprain. Interventions Participants were randomised to an accelerated intervention with early therapeutic exercise (exercise group) or a standard protection, rest, ice, compression, and elevation intervention (standard group). Main outcome measures The primary outcome was subjective ankle function (lower extremity functional scale). Secondary outcomes were pain at rest and on activity, swelling, and physical activity at baseline and at one, two, three, and four weeks after injury. Ankle function and rate of reinjury were assessed at 16 weeks. Results An overall treatment effect was in favour of the exercise group (P=0.0077); this was significant at both week 1 (baseline adjusted difference in treatment 5.28, 98.75% confidence interval 0.31 to 10.26; P=0.008) and week 2 (4.92, 0.27 to 9.57; P=0.0083). Activity level was significantly higher in the exercise group as measured by time spent walking (1.2 hours, 95% confidence interval 0.9 to 1.4 v 1.6, 1.3 to 1.9), step count (5621 steps, 95% confidence interval 4399 to 6843 v 7886, 6357 to 9416), and time spent in light intensity activity (53 minutes, 95% confidence interval 44 to 60 v 76, 58 to 95). The groups did not differ at any other time point for pain at rest, pain on activity, or swelling. The reinjury rate was 4% (two in each group). Conclusion An accelerated exercise protocol during the first week after ankle sprain improved ankle function; the group receiving this intervention was more active during that week than the group receiving standard care. Trial registration Current Controlled Trials ISRCTN13903946.
  • Publisher: England: British Medical Journal Publishing Group
  • Language: English
  • Identifier: ISSN: 0959-8138
    EISSN: 1468-5833
    EISSN: 1756-1833
    DOI: 10.1136/bmj.c1964
    PMID: 20457737
  • Source: BMJ Open Access Journals
    MEDLINE
    Alma/SFX Local Collection
    ProQuest Central

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