Language:

SARS-CoV-2 infection among hospitalised pregnant women and impact of different viral strains on COVID-19 severity in Italy: a national prospective population-based cohort study

BJOG : an international journal of obstetrics and gynaecology, 2022-01, Vol.129 (2), p.221 [Peer Reviewed Journal]

2021 John Wiley & Sons Ltd. ;2021. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the associated terms available at https://novel-coronavirus.onlinelibrary.wiley.com ;EISSN: 1471-0528 ;DOI: 10.1111/1471-0528.16980 ;PMID: 34687585

Digital Resources/Online E-Resources

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
SARS-CoV-2 infection among hospitalised pregnant women and impact of different viral strains on COVID-19 severity in Italy: a national prospective population-based cohort study
Author: Donati, S ; Corsi, E ; Maraschini, A ; Salvatore, M A
Subjects: Adult ; Cohort Studies ; Comorbidity ; COVID-19 - diagnosis ; COVID-19 - epidemiology ; COVID-19 - therapy ; COVID-19 Testing - methods ; COVID-19 Testing - statistics & numerical data ; Female ; Hospitalization - statistics & numerical data ; Hospitals, Maternity - statistics & numerical data ; Humans ; Intensive Care Units - statistics & numerical data ; Italy - epidemiology ; Pregnancy ; Pregnancy Complications, Infectious - diagnosis ; Pregnancy Complications, Infectious - epidemiology ; Pregnancy Complications, Infectious - therapy ; Pregnancy Outcome - epidemiology ; Premature Birth - epidemiology ; Risk Assessment - methods ; Risk Assessment - statistics & numerical data ; Risk Factors ; SARS-CoV-2 - genetics ; SARS-CoV-2 - isolation & purification ; Severity of Illness Index
Is Part Of: BJOG : an international journal of obstetrics and gynaecology, 2022-01, Vol.129 (2), p.221
Description: The primary aim of this article was to describe SARS-CoV-2 infection among pregnant women during the wild-type and Alpha-variant periods in Italy. The secondary aim was to compare the impact of the virus variants on the severity of maternal and perinatal outcomes. National population-based prospective cohort study. A total of 315 Italian maternity hospitals. A cohort of 3306 women with SARS-CoV-2 infection confirmed within 7 days of hospital admission. Cases were prospectively reported by trained clinicians for each participating maternity unit. Data were described by univariate and multivariate analyses. COVID-19 pneumonia, ventilatory support, intensive care unit (ICU) admission, mode of delivery, preterm birth, stillbirth, and maternal and neonatal mortality. We found that 64.3% of the cohort was asymptomatic, 12.8% developed COVID-19 pneumonia and 3.3% required ventilatory support and/or ICU admission. Maternal age of 30-34 years (OR 1.43, 95% CI 1.09-1.87) and ≥35 years (OR 1.62, 95% CI 1.23-2.13), citizenship of countries with high migration pressure (OR 1.75, 95% CI 1.36-2.25), previous comorbidities (OR 1.49, 95% CI 1.13-1.98) and obesity (OR 1.72, 95% CI 1.29-2.27) were all associated with a higher occurrence of pneumonia. The preterm birth rate was 11.1%. In comparison with the pre-pandemic period, stillbirths and maternal and neonatal deaths remained stable. The need for ventilatory support and/or ICU admission among women with pneumonia increased during the Alpha-variant period compared with the wild-type period (OR 3.24, 95% CI 1.99-5.28). Our results are consistent with a low risk of severe COVID-19 disease among pregnant women and with rare adverse perinatal outcomes. During the Alpha-variant period there was a significant increase of severe COVID-19 illness. Further research is needed to describe the impact of different SARS-CoV-2 viral strains on maternal and perinatal outcomes.
Publisher: England: John Wiley & Sons, Inc
Language: English
Identifier: EISSN: 1471-0528
DOI: 10.1111/1471-0528.16980
PMID: 34687585
Source: Coronavirus Research Database

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

SARS-CoV-2 infection among hospitalised pregnant women and impact of different viral strains on COVID-19 severity in Italy: a national prospective population-based cohort study

2021 John Wiley & Sons Ltd. ;2021. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the associated terms available at https://novel-coronavirus.onlinelibrary.wiley.com ;EISSN: 1471-0528 ;DOI: 10.1111/1471-0528.16980 ;PMID: 34687585

Searching Remote Databases, Please Wait