Language:

Inflammatory markers and exposure to airborne particles among workers in a Swedish pulp and paper mill

International archives of occupational and environmental health, 2016-07, Vol.89 (5), p.813-822 [Peer Reviewed Journal]

The Author(s) 2016 ;Springer-Verlag Berlin Heidelberg 2016 ;ISSN: 0340-0131 ;ISSN: 1432-1246 ;EISSN: 1432-1246 ;DOI: 10.1007/s00420-016-1119-5 ;PMID: 26875192

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Inflammatory markers and exposure to airborne particles among workers in a Swedish pulp and paper mill
Author: Westberg, Håkan ; Elihn, Karine ; Andersson, Eva ; Persson, Bodil ; Andersson, Lennart ; Bryngelsson, Ing-Liss ; Karlsson, Cathe ; Sjögren, Bengt
Subjects: Adult ; Aerosols - adverse effects ; Air Pollutants, Occupational - adverse effects ; Arbetsmedicin och miljömedicin ; Biomarkers ; Biomarkers - blood ; Blood Coagulation Factors - analysis ; C-reactive protein (CRP) ; C-Reactive Protein - analysis ; Dust - analysis ; Earth and Environmental Science ; Environment ; Environmental Health ; Environmental Health and Occupational Health ; Environmental Monitoring - methods ; Female ; Fibrinogen ; Health Sciences ; Human exposure ; Humans ; Hälsovetenskap ; IL-6 IL-8 and IL-10 ; Indoor air quality ; Inflammation ; Inflammation Mediators - blood ; Inhalation Exposure - adverse effects ; Interleukins (IL-1b ; Interleukins - blood ; Male ; Manufacturing Industry ; Medical and Health Sciences ; Medicin och hälsovetenskap ; Middle Aged ; Occupational Exposure - adverse effects ; Occupational health ; Occupational Medicine/Industrial Medicine ; Original ; Original Article ; Particulate Matter - adverse effects ; PM10 ; PM2.5 ; Pulp & paper mills ; Rehabilitation ; Respirable dust ; Serum amyloid A (SAA) ; Serum Amyloid A Protein - analysis ; Surveys and Questionnaires ; Sweden
Is Part Of: International archives of occupational and environmental health, 2016-07, Vol.89 (5), p.813-822
Description: Purpose To study the relationship between exposure to airborne particles in a pulp and paper mill and markers of inflammation and coagulation in blood. Methods Personal sampling of inhalable dust was performed for 72 subjects working in a Swedish pulp and paper mill. Stationary measurements were used to study concentrations of total dust, respirable dust, PM 10 and PM 2.5 , the particle surface area and the particle number concentrations. Markers of inflammation, interleukins (IL-1b, IL-6, IL-8, and IL-10), C-reactive protein (CRP), serum amyloid A (SAA), and fibrinogen and markers of coagulation factor VIII, von Willebrand, plasminogen activator inhibitor, and D-dimer were measured in plasma or serum. Sampling was performed on the last day of the work free period of 5 days, before and after the shift the first day of work and after the shifts the second and third day. In a mixed model analysis, the relationship between particulate exposures and inflammatory markers was determined. Sex, age, smoking, and BMI were included as covariates. Results The average 8-h time-weighted average (TWA) air concentration levels of inhalable dust were 0.30 mg/m 3 , range 0.005–3.3 mg/m 3 . The proxies for average 8-h TWAs of respirable dust were 0.045 mg/m 3 . Significant and consistent positive relations were found between several exposure metrics (PM 10, total and inhalable dust) and CRP, SAA and fibrinogen taken post-shift, suggesting a dose–effect relationship. Conclusion This study supports a relationship between occupational particle exposure and established inflammatory markers, which may indicate an increased risk of cardiovascular disease.
Publisher: Berlin/Heidelberg: Springer Berlin Heidelberg
Language: English
Identifier: ISSN: 0340-0131
ISSN: 1432-1246
EISSN: 1432-1246
DOI: 10.1007/s00420-016-1119-5
PMID: 26875192
Source: Springer Open Access
MEDLINE
SWEPUB Freely available online
ProQuest Central

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Inflammatory markers and exposure to airborne particles among workers in a Swedish pulp and paper mill

The Author(s) 2016 ;Springer-Verlag Berlin Heidelberg 2016 ;ISSN: 0340-0131 ;ISSN: 1432-1246 ;EISSN: 1432-1246 ;DOI: 10.1007/s00420-016-1119-5 ;PMID: 26875192

Searching Remote Databases, Please Wait