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New and continuing developments at PROSITE

Nucleic acids research, 2013-01, Vol.41 (Database issue), p.D344-D347 [Peer Reviewed Journal]

The Author(s) 2012. Published by Oxford University Press. 2012 ;ISSN: 0305-1048 ;EISSN: 1362-4962 ;DOI: 10.1093/nar/gks1067 ;PMID: 23161676

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Title:
New and continuing developments at PROSITE
Author: Sigrist, Christian J A ; de Castro, Edouard ; Cerutti, Lorenzo ; Cuche, Béatrice A ; Hulo, Nicolas ; Bridge, Alan ; Bougueleret, Lydie ; Xenarios, Ioannis
Subjects: Amino Acid Motifs ; Amino Acid Sequence ; Conserved Sequence ; Databases, Protein ; Internet ; Molecular Sequence Annotation ; Protein Structure, Tertiary ; Proteins - chemistry ; Proteins - classification ; Proteome - chemistry ; Sequence Analysis, Protein
Is Part Of: Nucleic acids research, 2013-01, Vol.41 (Database issue), p.D344-D347
Description: PROSITE (http://prosite.expasy.org/) consists of documentation entries describing protein domains, families and functional sites, as well as associated patterns and profiles to identify them. It is complemented by ProRule a collection of rules, which increases the discriminatory power of these profiles and patterns by providing additional information about functionally and/or structurally critical amino acids. PROSITE signatures, together with ProRule, are used for the annotation of domains and features of UniProtKB/Swiss-Prot entries. Here, we describe recent developments that allow users to perform whole-proteome annotation as well as a number of filtering options that can be combined to perform powerful targeted searches for biological discovery. The latest version of PROSITE (release 20.85, of 30 August 2012) contains 1308 patterns, 1039 profiles and 1041 ProRules.
Publisher: England: Oxford University Press
Language: English
Identifier: ISSN: 0305-1048
EISSN: 1362-4962
DOI: 10.1093/nar/gks1067
PMID: 23161676
Source: Geneva Foundation Free Medical Journals at publisher websites
Oxford University Press Open Access
MEDLINE
PubMed Central
DOAJ Directory of Open Access Journals

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New and continuing developments at PROSITE

The Author(s) 2012. Published by Oxford University Press. 2012 ;ISSN: 0305-1048 ;EISSN: 1362-4962 ;DOI: 10.1093/nar/gks1067 ;PMID: 23161676

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