Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007-2017

• Author: Einarson, Thomas R ; Acs, Annabel ; Ludwig, Craig ; Panton, Ulrik H
• Subjects: Adult ; Adults ; Aged ; Angina ; Angina pectoris ; Arteriosclerosis ; Bias ; Cardiovascular disease ; Cardiovascular diseases ; Cardiovascular Diseases - diagnosis ; Cardiovascular Diseases - epidemiology ; Cardiovascular Diseases - mortality ; Cause of Death ; Cerebral infarction ; Comorbidity ; Coronary artery ; Coronary artery disease ; Coronary vessels ; Data processing ; Diabetes ; Diabetes mellitus ; Diabetes mellitus (non-insulin dependent) ; Diabetes Mellitus, Type 2 - diagnosis ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetes Mellitus, Type 2 - mortality ; Fatalities ; Female ; Global Health - trends ; Health care policy ; Health risk assessment ; Heart attacks ; Heart diseases ; Heart failure ; Humans ; Hypertension ; Ischemia ; Ischemic heart disease ; Literature reviews ; Male ; Middle Aged ; Mortality ; Myocardial infarction ; Prevalence ; Prognosis ; Review ; Risk Factors ; Stroke ; Studies ; Time Factors ; Type 2 diabetes
• Is Part Of: Cardiovascular diabetology, 2018-06, Vol.17 (1), p.83-83, Article 83
• Description: Cardiovascular disease (CVD) is a common comorbidity in type 2 diabetes (T2DM). CVD's prevalence has been growing over time. To estimate the current prevalence of CVD among adults with T2DM by reviewing literature published within the last 10 years (2007-March 2017). We searched Medline, Embase, and proceedings of major scientific meetings for original research documenting the prevalence of CVD in T2DM. CVD included stroke, myocardial infarction, angina pectoris, heart failure, ischemic heart disease, cardiovascular disease, coronary heart disease, atherosclerosis, and cardiovascular death. No restrictions were placed on country of origin or publication language. Two reviewers independently searched for articles and extracted data, adjudicating results through consensus. Data were summarized descriptively. Risk of bias was examined by applying the STROBE checklist. We analyzed data from 57 articles with 4,549,481 persons having T2DM. Europe produced the most articles (46%), followed by the Western Pacific/China (21%), and North America (13%). Overall in 4,549,481 persons with T2DM, 52.0% were male, 47.0% were obese, aged 63.6 ± 6.9 years old, with T2DM duration of 10.4 ± 3.7 years. CVD affected 32.2% overall (53 studies, N = 4,289,140); 29.1% had atherosclerosis (4 studies, N = 1153), 21.2% had coronary heart disease (42 articles, N = 3,833,200), 14.9% heart failure (14 studies, N = 601,154), 14.6% angina (4 studies, N = 354,743), 10.0% myocardial infarction (13 studies, N = 3,518,833) and 7.6% stroke (39 studies, N = 3,901,505). CVD was the cause of death in 9.9% of T2DM patients (representing 50.3% of all deaths). Risk of bias was low; 80 ± 12% of STROBE checklist items were adequately addressed. Globally, overall CVD affects approximately 32.2% of all persons with T2DM. CVD is a major cause of mortality among people with T2DM, accounting for approximately half of all deaths over the study period. Coronary artery disease and stroke were the major contributors.
  
• Publisher: England: BioMed Central
  
• Language: English
  
• Identifier: ISSN: 1475-2840
  EISSN: 1475-2840
  DOI: 10.1186/s12933-018-0728-6
  PMID: 29884191
  
• Source: DOAJ Directory of Open Access Journals
  GFMER Free Medical Journals
  MEDLINE
  PubMed Central
  Springer Nature OA/Free Journals
  ROAD: Directory of Open Access Scholarly Resources
  ProQuest Central