Ngôn ngữ:

Age, Neuropathology, and Dementia

The New England journal of medicine, 2009-05, Vol.360 (22), p.2302-2309 [Tạp chí có phản biện]

Copyright © 2009 Massachusetts Medical Society. All rights reserved. ;2009 INIST-CNRS ;2009 Massachusetts Medical Society ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa0806142 ;PMID: 19474427 ;CODEN: NEJMAG

Tài liệu số/Tài liệu điện tử

Trích dẫn Trích dẫn bởi

Gửi đến

Nhan đề:
Age, Neuropathology, and Dementia
Tác giả: Savva, George M ; Wharton, Stephen B ; Ince, Paul G ; Forster, Gillian ; Matthews, Fiona E ; Brayne, Carol
Chủ đề: Age ; Age Factors ; Aged ; Aged, 80 and over ; Aging - pathology ; Alzheimer Disease - pathology ; Alzheimer's disease ; Alzheimers disease ; Atrophy - pathology ; Autopsy ; Biological and medical sciences ; Brain - pathology ; Causes of ; Cerebrovascular Disorders - pathology ; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases ; Dementia ; Dementia - pathology ; Donations ; Female ; General aspects ; Humans ; Interviews ; Lewy Bodies - pathology ; Logistic regression ; Male ; Medical sciences ; Neurology ; Odds Ratio ; Older people ; Plaque, Amyloid - pathology ; Population ; Psychological aspects
Là 1 phần của: The New England journal of medicine, 2009-05, Vol.360 (22), p.2302-2309
Mô tả: In this longitudinal study of cognitive function and aging, which included 456 participants who agreed to post-mortem brain examination and died between 69 and 103 years of age, the relationship between the pathological features of Alzheimer's disease and clinical dementia at the time of death was attenuated in the oldest old persons. For example, the odds ratio for the association between dementia and neocortical neuritic plaques was 8.6 at 75 years of age but only 2.5 at 95 years of age. In this study of cognitive function and aging, the relationship between the postmortem pathological features of Alzheimer's disease and clinical dementia at the time of death was attenuated in the oldest old persons. For example, the odds ratio for the association between dementia and neocortical neuritic plaques was 8.6 at 75 years of age but only 2.5 at 95 years of age. During the 20th century, interest in the dementias focused on specific disorders defined by criteria that were developed for patients who had onset of dementia before the age of 65 years, which had come to be considered by many as pathologically distinct from late-onset dementia. 1 In the second half of that century, the distinction between early-onset and late-onset dementias was challenged by the realization that the hallmarks of Alzheimer's disease in older persons were indistinguishable from those in younger persons with Alzheimer's disease. 2 Population epidemiologic studies of dementia have revealed a relentless rise in the incidence of dementia into old . . .
Nơi xuất bản: Waltham, MA: Massachusetts Medical Society
Ngôn ngữ: English
Số nhận dạng: ISSN: 0028-4793
EISSN: 1533-4406
DOI: 10.1056/NEJMoa0806142
PMID: 19474427
CODEN: NEJMAG
Nguồn: ProQuest One Psychology
MEDLINE
Alma/SFX Local Collection
ProQuest Central

Trở lại danh sách kết quả

Trước Kết quả 5 Tiếp theo Tới trang tiếp theo


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Age, Neuropathology, and Dementia

Copyright © 2009 Massachusetts Medical Society. All rights reserved. ;2009 INIST-CNRS ;2009 Massachusetts Medical Society ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa0806142 ;PMID: 19474427 ;CODEN: NEJMAG

Đang tìm Cơ sở dữ liệu bên ngoài...