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Neosiphoniamolide A, a Novel Cyclodepsipeptide, with Antifungal Activity from the Marine Sponge Neosiphonia superstes

Journal of natural products (Washington, D.C.), 1995-01, Vol.58 (1), p.121-123 [Peer Reviewed Journal]

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Title:
Neosiphoniamolide A, a Novel Cyclodepsipeptide, with Antifungal Activity from the Marine Sponge Neosiphonia superstes
Author: D'Auria, M. Valeria ; Paloma, Luigi Gomez ; Minale, Luigi ; Zampella, Angela ; Debitus, Cécile ; Perez, Joseph
Subjects: Animals ; Antifungal Agents - chemistry ; Antifungal Agents - isolation & purification ; Antifungal Agents - pharmacology ; Magnetic Resonance Spectroscopy ; Marine ; Microbial Sensitivity Tests ; Neosiphonia superstes ; Peptides, Cyclic - chemistry ; Peptides, Cyclic - isolation & purification ; Peptides, Cyclic - pharmacology ; Porifera ; Porifera - chemistry
Is Part Of: Journal of natural products (Washington, D.C.), 1995-01, Vol.58 (1), p.121-123
Description: A novel cyclodepsipeptide, neosiphoniamolide A [1], has been isolated from the sponge Neosiphonia superstes. The structure of 1, which contains a 12-carbon hydroxy acid, glycine, valine, and a halogenated tyrosine residue in an 18-membered ring, is related to jaspamide and the geodiamolides, previously isolated from sponges. The structure was solved by spectroscopic analysis.
Publisher: United States: American Chemical Society
Language: English
Identifier: ISSN: 0163-3864
EISSN: 1520-6025
DOI: 10.1021/np50115a017
PMID: 7760068
Source: MEDLINE
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