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Long-Term Survival of the Very Elderly Undergoing Coronary Artery Bypass Grafting

The Annals of thoracic surgery, 2008-04, Vol.85 (4), p.1233-1237 [Peer Reviewed Journal]

The Society of Thoracic Surgeons ;2008 The Society of Thoracic Surgeons ;2008 INIST-CNRS ;ISSN: 0003-4975 ;EISSN: 1552-6259 ;DOI: 10.1016/j.athoracsur.2007.12.066 ;PMID: 18355501 ;CODEN: ATHSAK

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Title:
Long-Term Survival of the Very Elderly Undergoing Coronary Artery Bypass Grafting
Author: Likosky, Donald S., PhD ; Dacey, Lawrence J., MD ; Baribeau, Yvon R., MD ; Leavitt, Bruce J., MD ; Clough, Robert, MD ; Cochran, Richard P., MD ; Quinn, Reed, MD ; Sisto, Donato A., MD ; Charlesworth, David C., MD ; Malenka, David J., MD ; MacKenzie, Todd A., PhD ; Olmstead, Elaine M., BA ; Ross, Cathy S., MS ; O’Connor, Gerald T., DSc, PhD
Subjects: Age Factors ; Aged, 80 and over ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Cardiology. Vascular system ; Cardiothoracic Surgery ; Cohort Studies ; Confidence Intervals ; Coronary Angiography ; Coronary Artery Bypass - methods ; Coronary Artery Bypass - mortality ; Coronary Disease - diagnostic imaging ; Coronary Disease - mortality ; Coronary Disease - surgery ; Coronary heart disease ; Female ; Follow-Up Studies ; Geriatric Assessment ; Heart ; Humans ; Kaplan-Meier Estimate ; Male ; Medical sciences ; New England ; Pneumology ; Probability ; Proportional Hazards Models ; Prospective Studies ; Risk Assessment ; Severity of Illness Index ; Surgery ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the heart ; Survival Analysis ; Time Factors
Is Part Of: The Annals of thoracic surgery, 2008-04, Vol.85 (4), p.1233-1237
Description: Background Increasing numbers of the very elderly are undergoing coronary artery bypass graft surgery (CABG). Short-term results have been studied, but few data are available concerning long-term outcomes. Methods We conducted a cohort study of 54,397 consecutive patients undergoing primary, isolated CABG surgery between July 1, 1987, and June 30, 2006. Patient records were linked to the Social Security Administration’s Death Master File. Results During 390,871 person-years of follow-up, there were 17,352 deaths. There were 51,149 patients younger than 80 years, 2,661 patients aged 80 to 84 years, and 587 patients aged 85 or more years who underwent isolated CABG surgery. Crude in-hospital survival was 97.2% for those less than 80 years, 98.3% for those aged 80 to 84 years, and 87.6% for those aged 85 or more years. Patients aged 80 or more years were more likely to be female (46.9%), more likely to be emergency priority (10.2%), and more likely to have associated comorbidities than younger patients. Patients aged 85 or more years were more likely to have intraoperative and postoperative morbid events. Among patients younger than 80, median survival was 14.4 years with an annual incidence of death of 4.2%. Among patients 80 to 84 years old, median survival time was 7.4 years, with an annual incidence rate of death of 10.3%. Among patients aged 85 or more years, median survival was 5.8 years, and the annual incidence of death was 13.7%. Conclusions Although very elderly CABG patients have more comorbidities and more acute presentation than younger patients and their in-hospital mortality rate is high, their long-term survival is surprisingly good.
Publisher: New York, NY: Elsevier Inc
Language: English
Identifier: ISSN: 0003-4975
EISSN: 1552-6259
DOI: 10.1016/j.athoracsur.2007.12.066
PMID: 18355501
CODEN: ATHSAK
Source: GFMER Free Medical Journals
MEDLINE
Alma/SFX Local Collection

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Long-Term Survival of the Very Elderly Undergoing Coronary Artery Bypass Grafting

The Society of Thoracic Surgeons ;2008 The Society of Thoracic Surgeons ;2008 INIST-CNRS ;ISSN: 0003-4975 ;EISSN: 1552-6259 ;DOI: 10.1016/j.athoracsur.2007.12.066 ;PMID: 18355501 ;CODEN: ATHSAK

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