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Epigenetic basis of Alzheimer disease

World journal of biological chemistry, 2020-09, Vol.11 (2), p.62-75

The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. 2020 ;ISSN: 1949-8454 ;EISSN: 1949-8454 ;DOI: 10.4331/wjbc.v11.i2.62 ;PMID: 33024518

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  • Title:
    Epigenetic basis of Alzheimer disease
  • Author: Tecalco-Cruz, Angeles C ; Ramírez-Jarquín, Josué O ; Alvarez-Sánchez, María E ; Zepeda-Cervantes, Jesus
  • Subjects: Minireviews
  • Is Part Of: World journal of biological chemistry, 2020-09, Vol.11 (2), p.62-75
  • Description: Alzheimer disease (AD) is the primary form of dementia that occurs spontaneously in older adults. Interestingly, the epigenetic profile of the cells forming the central nervous system changes during aging and may contribute to the progression of some neurodegenerative diseases such as AD. In this review, we present general insights into relevant epigenetic mechanisms and their relationship with aging and AD. The data suggest that some epigenetic changes during aging could be utilized as biomarkers and target molecules for the prevention and control of AD.
  • Publisher: Baishideng Publishing Group Inc
  • Language: English
  • Identifier: ISSN: 1949-8454
    EISSN: 1949-8454
    DOI: 10.4331/wjbc.v11.i2.62
    PMID: 33024518
  • Source: GFMER Free Medical Journals
    PubMed Central
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