Ngôn ngữ:

Adult haemophagocytic syndrome

The Lancet (British edition), 2014-04, Vol.383 (9927), p.1503-1516 [Tạp chí có phản biện]

Elsevier Ltd ;2014 Elsevier Ltd ;2015 INIST-CNRS ;Copyright © 2014 Elsevier Ltd. All rights reserved. ;Copyright Elsevier Limited Apr 26, 2014 ;ISSN: 0140-6736 ;EISSN: 1474-547X ;DOI: 10.1016/S0140-6736(13)61048-X ;PMID: 24290661 ;CODEN: LANCAO

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Nhan đề:
Adult haemophagocytic syndrome
Tác giả: Ramos-Casals, Manuel, MD ; Brito-Zerón, Pilar, MD ; López-Guillermo, Armando, MD ; Khamashta, Munther A, Prof ; Bosch, Xavier, Dr
Chủ đề: Adult ; Autoimmune diseases ; Bacterial infections ; Biological and medical sciences ; Cancer ; Cancer therapies ; Cytomegalovirus ; Disease ; Drug dosages ; Epidemiology ; General aspects ; Global Health ; Hematologic and hematopoietic diseases ; Hematology ; Herpes viruses ; Humans ; Incidence ; Infections ; Influenza ; Internal Medicine ; Lupus ; Lymphohistiocytosis, Hemophagocytic - diagnosis ; Lymphohistiocytosis, Hemophagocytic - epidemiology ; Lymphohistiocytosis, Hemophagocytic - etiology ; Lymphohistiocytosis, Hemophagocytic - therapy ; Medical sciences ; Mortality ; Other diseases. Hematologic involvement in other diseases ; Polymethyl methacrylate ; Tuberculosis ; Tumors ; Viral infections
Là 1 phần của: The Lancet (British edition), 2014-04, Vol.383 (9927), p.1503-1516
Mô tả: Summary Haemophagocytic syndromes (haemophagocytic lymphohistiocytosis) have a wide range of causes, symptoms, and outcomes, but all lead to a hyperinflammatory response and organ damage—mainly reported in paediatric patients, but reports of adult presentation are increasing. Analysis of the genetic and molecular pathophysiology of these syndromes have improved the understanding of the crosstalk between lymphocytes and histiocytes and their regulatoty mechanisms. Clinical presentations with a broad differential diagnosis, and often life-threatening outcome, complicate the management, which might include supportive intensive care, immunosuppressive and biological treatments, or haemopoietic stem cell transplantation. Insufficient knowledge of these syndromes could contribute to poor prognosis. Early diagnosis is essential to initiate appropriate treatment and improve the quality of life and survival of patients with this challenging disorder.
Nơi xuất bản: Kidlington: Elsevier Ltd
Ngôn ngữ: English
Số nhận dạng: ISSN: 0140-6736
EISSN: 1474-547X
DOI: 10.1016/S0140-6736(13)61048-X
PMID: 24290661
CODEN: LANCAO
Nguồn: ProQuest One Psychology
AUTh Library subscriptions: ProQuest Central
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Adult haemophagocytic syndrome

Elsevier Ltd ;2014 Elsevier Ltd ;2015 INIST-CNRS ;Copyright © 2014 Elsevier Ltd. All rights reserved. ;Copyright Elsevier Limited Apr 26, 2014 ;ISSN: 0140-6736 ;EISSN: 1474-547X ;DOI: 10.1016/S0140-6736(13)61048-X ;PMID: 24290661 ;CODEN: LANCAO

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