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A patient with Turner syndrome received the percutaneous vertebroplasty seven times: a case report and literature review

European journal of medical research, 2021-12, Vol.26 (1), p.139-139, Article 139 [Peer Reviewed Journal]

2021. The Author(s). ;COPYRIGHT 2021 BioMed Central Ltd. ;2021. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2021 ;ISSN: 2047-783X ;ISSN: 0949-2321 ;EISSN: 2047-783X ;DOI: 10.1186/s40001-021-00617-4 ;PMID: 34876225

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Title:
A patient with Turner syndrome received the percutaneous vertebroplasty seven times: a case report and literature review
Author: Li, Longyu ; Shi, Yifang ; Zhao, Nan ; Liu, Zhengpei ; Zhao, Zhe ; Song, Zongmian ; Zheng, Sailei ; Yan, Miaoheng ; Leng, Zikuan ; Chen, Songfeng ; Shang, Guowei ; Kou, Hongwei ; Liu, Hongjian
Subjects: Aged ; Aging ; Amenorrhea ; Back pain ; Bacteria ; Cardiovascular disease ; Case Report ; Chromosomes ; Estrogen ; Estrogens ; Female ; Fractures ; Fractures, Compression - diagnosis ; Fractures, Compression - etiology ; Genetic disorders ; Gut microbiome ; Hormone therapy ; Hospitals ; Humans ; Metabolism ; Microbiota ; Orthopedic surgery ; Osteoporosis ; Osteoporotic Fractures - diagnosis ; Osteoporotic Fractures - etiology ; Osteoporotic Fractures - surgery ; Ovaries ; Patients ; Percutaneous vertebroplasty ; Povidone ; Radiography ; Rare diseases ; Reoperation - statistics & numerical data ; Thoracic Vertebrae - diagnostic imaging ; Thoracic Vertebrae - injuries ; Thoracic Vertebrae - surgery ; Tumor necrosis factor-TNF ; Turner syndrome ; Turner Syndrome - complications ; Turner Syndrome - diagnosis ; Turner Syndrome - genetics ; Ultrasonic imaging ; Uterus ; Vertebral compression fractures ; Vertebroplasty - adverse effects ; Womens health
Is Part Of: European journal of medical research, 2021-12, Vol.26 (1), p.139-139, Article 139
Description: Turner syndrome (TS) is characterized as the complete or partial absence of one X chromosome and is an extremely rare disease affecting approximately 1:2500 live female births. Though the prevalence of osteoporosis among women with TS is estimated to be around 55-64% and they suffer more frequently from fractures than normal, few reports concerning TS patients with osteoporosis are able to be seen due to tiny number of patients. Here, we report a rare case of TS with osteoporosis, who has undergone percutaneous vertebroplasty (PVP) seven times because of several vertebral compression fractures (VCFs). G-banded karyotype analysis was performed and the result was 45,X[43]/47,XXX[17], indicating that the patient was a mosaicism of TS karyotype and Trisomy X syndrome karyotype. TS is the underlying cause of low level of estrogen for this patient. The interaction of aging, estrogen deficiency and intestinal dysbacteriosis leads to her severe osteoporosis and multi-segmental VCFs. The aim of this report is to provide recommendations regarding the management of TS patients with osteoporosis by reviewing the clinical presentation of TS, the influence of estrogen deficiency in osteoporosis, etc. CONCLUSIONS: Early diagnosis and hormone replacement treatment are essential for TS patients to prevent osteoporosis and reduce the risk of fractures. This is a rare case report describing TS patient with severe osteoporosis and VCFs.
Publisher: England: BioMed Central Ltd
Language: English
Identifier: ISSN: 2047-783X
ISSN: 0949-2321
EISSN: 2047-783X
DOI: 10.1186/s40001-021-00617-4
PMID: 34876225
Source: Open Access: DOAJ Directory of Open Access Journals
AUTh Library subscriptions: ProQuest Central
MEDLINE
Springer Open Access Journals
NCBI PubMed Central（免费）

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A patient with Turner syndrome received the percutaneous vertebroplasty seven times: a case report and literature review

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