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0.025-inch vs 0.035-inch guide wires for wire-guidedcannulation during endoscopic retrograde cholangiopancreatography： A randomized study

世界胃肠病学杂志：英文版（电子版）, 2015 (30), p.9182-9188

ISSN: 1007-9327 ;EISSN: 2219-2840

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  • Title:
    0.025-inch vs 0.035-inch guide wires for wire-guidedcannulation during endoscopic retrograde cholangiopancreatography： A randomized study
  • Subjects: bileduct ; cannulation ; cholangiopancreatography; Guide ; Endoscopic ; pancreatitis ; Post-endoscopic ; retrograde ; retrogradecholangiopancreatography ; Selective ; wire ; Wire-guided
  • Is Part Of: 世界胃肠病学杂志：英文版（电子版）, 2015 (30), p.9182-9188
  • Description: AIM To compare the clinical outcomes between0.025-inch and 0.035-inch guide wires （GWs） whenused in wire-guided cannulation （WGC）.METHODS： A single center, randomized study wasconducted between April 2011 and March 2013. Thisstudy was approved by the Medical Ethics Committeeat our hospital. Informed, written consent wasobtained from each patient prior to study enrollment.Three hundred and twenty-two patients with a na？vepapilla of Vater who underwent endoscopic retrogradecholangiopancreatography （ERCP） for the purpose ofselective bile duct cannulation with WGC were enrolledin this study. Fifty-three patients were excluded basedon the exclusion criteria, and 269 patients wererandomly allocated to two groups by a computer andanalyzed： the 0.025-inch GW group （n = 109） and the0.035-inch GW group （n = 160）. The primary endpointwas the success rate of selective bile duct cannulationwith WGC. Secondary endpoints were the successrates of the pancreatic GW technique and precutting,selective bile duct cannulation time, ERCP proceduretime, the rate of pancreatic duct stent placement, thefinal success rate of selective bile duct cannulation, and the incidence of post-ERCP pancreatitis （PEP）.RESULTS： The primary success rates of selective bileduct cannulation with WGC were 80.7% （88/109） and86.3% （138/160） for the 0.025-inch and the 0.035-inchgroups, respectively （P = 0.226）. There were nostatistically significant differences in the success rates ofselective bile duct cannulation using the pancreatic ductGW technique （46.7% vs 52.4% for the 0.025-inch and0.035-inch groups, respectively; P = 0.884） or in thesuccess rates of selective bile duct cannulation usingprecutting （66.7% vs 63.6% for the 0.025-inch and0.035-inch groups, respectively; P = 0.893）. The finalsuccess rates for selective bile duct cannulation usingthese procedures were 92.7% （101/109） and 97.5%（156/160） for the 0.025-inch and 0.035-inch groups,respectively （P = 0.113）. There were no significantdifferences in selective bile duct cannulation time（median ± interquartile range： 3.7 ± 13.9 min vs 4.0± 11.2 min for the 0.025-inch and 0.035-inch groups,respectively; P = 0.851）, ERCP procedure time （median± interquartile range： 32 ± 29 min vs 30 ± 25 min forthe 0.025-inch and 0.035-inch groups, respectively; P =0.184） or in the rate of pancreatic duct stent placement（14.7% vs 15.6% for the 0.025-inch and 0.035-inchgroups, respectively; P = 0.832）. The incidence of PEPwas 2.8% （3/109） and 2.5% （4/160） for the 0.025-inchand 0.035-inch groups, respectively （P = 0.793）.CONCLUSION： The thickness of the GW for WGC doesnot appear to affect either the success rate of selectivebile duct cannulation or the incidence of PEP.
  • Language: English
  • Identifier: ISSN: 1007-9327
    EISSN: 2219-2840
  • Source: Freely Accessible Journals
    Open Access: PubMed Central
    Alma/SFX Local Collection
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