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C-Reactive Protein, Fibrinogen, and Cardiovascular Disease Prediction

The New England journal of medicine, 2012, Vol.367 (14), p.1310-1320 [Peer Reviewed Journal]

Copyright © 2012 Massachusetts Medical Society. All rights reserved. ;info:eu-repo/semantics/closedAccess ;2015 INIST-CNRS ;Copyright © 2012 Massachusetts Medical Society. 2012 ;Wageningen University & Research ;ISSN: 0028-4793 ;ISSN: 1533-4406 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa1107477 ;PMID: 23034020 ;CODEN: NEJMAG

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Title:
C-Reactive Protein, Fibrinogen, and Cardiovascular Disease Prediction
Author: Kaptoge, S ; Di Angelantonio, E ; Pennells, L ; Wood, AM ; White, IR ; Gao, P ; Walker, M ; Thompson, A ; Sarwar, N ; Caslake, M ; Butterworth, AS ; Amouyel, P ; Assmann, G ; Bakker, SJL ; Barr, ELM ; Barrett-Connor, E ; Benjamin, EJ ; Bjorkelund, C ; Brenner, H ; Brunner, E ; Clarke, R ; Cooper, JA ; Cremer, P ; Cushman, M ; Dagenais, GR ; D'Agostino, RB ; Dankner, R ; Davey-Smith, G ; Deeg, D ; Dekker, JM ; Engstrom, G ; Folsom, AR ; Fowkes, FGR ; Gallacher, J ; Gaziano, JM ; Giampaoli, S ; Gillum, RF ; Hofman, Bert ; Howard, BV ; Ingelsson, E ; Iso, H ; Jorgensen, T ; Kiechl, S ; Kitamura, A ; Kiyohara, Y ; Koenig, W ; Kromhout, D ; Kuller, LH ; Lawlor, DA ; Meade, TW ; Nissinen, A ; Nordestgaard, BG ; Onat, A ; Panagiotakos, DB ; Psaty, BM ; Roiguez, B ; Rosengren, A ; Salomaa, V ; Kauhanen, J ; Salonen, JT ; Shaffer, JA ; Shea, S ; Ford, I ; Stehouwer, CDA ; Strandberg, TE ; Tipping, RW ; Tosetto, A ; Wassertheil-Smoller, S ; Wennberg, P ; Westendorp, RG ; Whincup, PH ; Wilhelmsen, L ; Woodward, M ; Lowe, GDO ; Wareham, NJ ; Khaw, KT ; Sattar, N ; Packard, CJ ; Gudnason, V ; Ridker, PM ; Pepys, MB ; Thompson, SG ; Danesh, J
Subjects: Adult ; association ; Biological and medical sciences ; Biomarkers ; Biomarkers - blood ; Blood pressure ; C-reactive protein ; C-Reactive Protein - metabolism ; Cardiac and Cardiovascular Systems ; Cardiovascular disease ; Cardiovascular diseases ; Cardiovascular Diseases - blood ; Cardiovascular Diseases - prevention & control ; Care and treatment ; Cholesterol ; Clinical Medicine ; Cohort Studies ; coronary-heart-disease ; cost-effectiveness ; Data processing ; Diabetes mellitus ; Diagnosis ; Female ; Fibrinogen ; Fibrinogen - metabolism ; General aspects ; Health aspects ; Heart attacks ; Humans ; inflammation ; Kardiologi ; Klinisk medicin ; Lipids - blood ; Male ; Mass Screening ; Medical and Health Sciences ; Medical sciences ; Medicin och hälsovetenskap ; metaanalysis ; Middle Aged ; nonvascular mortality ; practice guidelines ; Practice Guidelines as Topic ; primary prevention ; Prognosis ; Proportional Hazards Models ; Reclassification ; Risk Factors ; risk profile ; SDG 3 - Good Health and Well-being ; Smoking ; statin therapy
Is Part Of: The New England journal of medicine, 2012, Vol.367 (14), p.1310-1320
Description: In a pooled analysis of data from nearly 250,000 people from 52 studies, the authors estimated the incremental value of C-reactive protein or fibrinogen level for the prediction of cardiovascular risk when added to standard models of risk prediction. There is an evolving debate about the value of assessing levels of C-reactive protein (CRP) and other soluble biomarkers of inflammation for the prediction of first cardiovascular events. In 2003, the Centers for Disease Control and Prevention and the American Heart Association (AHA) concluded that CRP may be used at the discretion of a physician as part of a global assessment of cardiovascular risk. 1 In 2007, the European Society of Cardiology described as “premature” the incorporation of CRP assessment into standard models for the prediction of cardiovascular risk. 2 In 2009, the Canadian Cardiovascular Society recommended CRP assessment in patients at . . .
Publisher: Waltham, MA: Massachusetts Medical Society
Language: English
Identifier: ISSN: 0028-4793
ISSN: 1533-4406
EISSN: 1533-4406
DOI: 10.1056/NEJMoa1107477
PMID: 23034020
CODEN: NEJMAG
Source: NARCIS

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C-Reactive Protein, Fibrinogen, and Cardiovascular Disease Prediction

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