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Inflammation, Aging, and Cardiovascular Disease: JACC Review Topic of the Week

Journal of the American College of Cardiology, 2022-03, Vol.79 (8), p.837-847 [Peer Reviewed Journal]

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Title:
Inflammation, Aging, and Cardiovascular Disease: JACC Review Topic of the Week
Author: Liberale, Luca ; Badimon, Lina ; Montecucco, Fabrizio ; Lüscher, Thomas F ; Libby, Peter ; Camici, Giovanni G
Subjects: Aging ; Cardiovascular Diseases - etiology ; Humans ; Inflammation - complications
Is Part Of: Journal of the American College of Cardiology, 2022-03, Vol.79 (8), p.837-847
Description: Aging and inflammation both contribute pivotally to cardiovascular (CV) and cerebrovascular disease, the leading causes of death and disability worldwide. The concept of inflamm-aging recognizes that low-grade inflammatory pathways observed in the elderly contribute to CV risk. Understanding the mechanisms that link inflammation and aging could reveal new therapeutic targets and offer options to cope with the growing aging population worldwide. This review reports recent scientific advances in the pathways through which inflamm-aging mediates age-dependent decline in CV function and disease onset and considers critically the translational potential of such concepts into everyday clinical practice.
Publisher: United States
Language: English
Identifier: ISSN: 0735-1097
EISSN: 1558-3597
DOI: 10.1016/j.jacc.2021.12.017
PMID: 35210039
Source: GFMER Free Medical Journals
MEDLINE
Alma/SFX Local Collection

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